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Maturation Phenomenon in Cerebral Ischemia V - Fifth International Workshop April 28-May 1, 2002 Banff, Alberta, Canada (Paperback)
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Maturation Phenomenon in Cerebral Ischemia V - Fifth International Workshop April 28-May 1, 2002 Banff, Alberta, Canada (Paperback)
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The Maturation Phenomenon, first described by Ito et al. in 1975,
refers to post ischemic changes that develop hours or days after an
ischemic insult. The delayed neuronal death of CAl pyramidal cells
of the hippocampus is a classic example. The report of the
phenomenon boosted research in the field, as it became evi dent
that ischemic damage is not a sudden event but a process
potentially suscep tible to therapeutic intervention. In September
1990, Ito and collaborators organized the First International Sym
posium on "Maturation Phenomenon in Cerebral Ischemia" which was
held in To kyo, Japan. The Second Symposium was organized in Tokyo,
Japan in March/April 1996. The Third Symposium was held in
Pozzilli, Italy in April 1998 and the Fourth Symposium was held in
New Orleans, Louisiana, USA in October/Novem ber 1999. This book
contains the presentations of the Fifth International Workshop on
Maturation Phenomenon in Cerebral Ischemia held at the Rimrock
Resort Ho tel in Banff, Alberta, Canada on April 28-May 1, 2002. It
outlines the present sta tus of investigations and provides further
stimulation for research in this field. The Maturation Phenomenon
represents a continuing struggle for survival be tween the
acceleration of tissue or neuronal death and the activation of
defense mechanisms leading to neuronal recovery. The elucidation of
these mechanisms is important for developing the ability to
manipulate them during a long-lasting "therapeutic window".
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