Occult atherosclerotic diseases impose great challenges in the
cardiovascular practice. Although their pathology is not much
different from that of the overt group of diseases, the clinical
approach to their diagnoses remains a puzzle. This has mainly
emerged as a result of the problems faced in trying to pick up the
vulnerable subjects from among the general public. More definitive
candidates to be evaluated are those belonging to one of the high
risk groups. There are no statistical figures available on the
incidence of occult atherosclerotic disease in the "non risky"
general public and this is definitely an area that needs further
investigation. Atherosclerotic disease whether they are in the
cerebral, coronary, renal or lower limb arteries are theoretically
interrelated because the basic patho logical changes are usually
similar. However there still remain some differ ences which are
mainly due to variation in the flow pattern in the arteries. Thus
it will be important clinically and from the management point of
view to investigate for the presence of occult disease in other
arteries if an atherosclerotic disease in a certain artery has been
discovered. This approach is of a great significance especially
from the preventive point of view in order to avoid catastrophic
events which may have resulted from pathology in the other region."
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