Chris Barnard needed the help of exceptional men and women to stay ahead of the fast-developing science of transplantation. One of these exceptional men were Winston Wicomb, the darker brother of the famous Randall.

He had to be hidden as a child to prevent the Apartheid inspectors from discovering his family’s racial identity. He had to endure the rampant racism that existed in South Africa at school and in the army… Winston, who had to fix cars in the backyard to make ends meet, had a curious encounter with Chris Barnard and got appointed in his research laboratory. Winston had to develop an apparatus with which hearts could be kept alive to enable transport.

This is the story of an unlikely hero; a man who changed transplantation forever, and a South African citizen who never got the recognition he deserved.

It’s a story of perseverance. And hope. Even... love.

This open access book presents the diagnosis, investigation and treatment of neurovascular diseases, and offers expert opinions and advice on avoiding complications in neurovascular surgery. It also covers complication management and post-operative follow-up care. The book is divided in to three parts; the first part discusses common approaches in neurovascular surgery, describing the steps, indications for and limitations of the approach, as well as the associated complications and how to avoid them. The second part addresses surgical treatment based on pathology, taking the different locations of lesions into consideration. The third part focuses on the technological developments that support neurovascular surgery, which may not be available everywhere, but have been included to help vascular surgeon understand the principles. This book is a guide for young neurosurgeons, neurosurgery residents and neurosurgery fellows, as well as for medical students and nurses who are interested in neurosurgery or are associated with this field in any way. It is also a useful teaching aid for senior neurosurgeons.

Atlas of Organ Transplantation, Second Edition, provides the reader with a comprehensive and pictorial step-by-step account of abdominal organ transplant procedures performed by contemporary transplant surgeons today. Emphasis is placed on newer procedures or procedures that have undergone significant modifications. It is recognized that there are many well-accepted techniques for the same procedure, with each having potential merit. While it is impossible to present all of these variations, an attempt is made to describe the common variations in surgical technique and common variation in procedure based on anatomical variations. Written by an expert in the field, Atlas of Organ Transplantation, Second Edition, includes schematic diagrams and high-quality intraoperative photographs, allowing readers to clearly visualize the course of the operative procedure. This format provides the reader with a clear visual and written description of all major transplant procedures in one reference book.

This book explains how hypertension affects 20-50% of the adult population in developed countries. Heart failure is the result of the hypertension's effects on the heart and it represents a growing public health problem. In this context the international scientific community is continuously struggling to develop better strategies in screening, diagnosing and treating hypertension and its deleterious effects. Thus, this field is continuously changing, with new important information being added constantly. This volume will offer both insights into the intimate mechanisms of transition from hypertension to heart failure and clinical practice advice on the prevention and treatment of heart failure in hypertensive population. The mechanisms which explain the progression from hypertension to heart failure will be also covered exhaustively by offering two chapters referring to the diagnosis of heart failure in hypertensive population and one regarding echocardiography which is the most frequently used imaging method in clinical practice. The reader will be also provided with information on cardiovascular magnetic resonance which has the unique advantage of differentiating hypertensive heart failure from other pathologies associated with increased myocardial thickness. This book is a useful tool for clinicians but also to the research community interested in heart failure and consequences of hypertension on heart who want to be up-to-date with the new developments in the field.

This book is designed to provide the practicing interventionist with a comprehensive list of procedural reports that covers the vast majority of the currently performed interventional procedures outside the cardiac system. It offers up-to-date explanatory notes, synopsis of the indications, contraindications and potential complications in an organized and practical format that follows the various body systems and progresses from the simple image guided FNA to the most complex procedures and incorporates the current societal guidelines. The book is divided for ease of reference into three main parts: Non vascular, Vascular and Neurovascular interventions. This information is not currently available in any single publication. The text provides residents, fellows as well as staff members with a quick, detailed and user-friendly resource for documentation of image-guided interventional procedures that will facilitate their tasks, improve the standard of documentation and reduce errors. The text can serve as a valuable tool for a quick review prior to a procedure or in preparation for an oral board certifying examination. The entries are vetted by recognized experts in the field of image-guided intervention. Procedural Dictations in Image-Guided Intervention: Non-Vascular, Vascular & Neuro Interventions covers the vast majority of the currently practiced image-guided interventions in the various body systems. This information is supported by up-to-date references and international guidelines. This book is a must-have for residents and fellows undergoing training and all specialists in image-guided intervention.

This book describes a wide range of interventional procedures currently employed in the treatment of cardiac diseases in women with the aim of enabling not only interventional cardiologists but also cardiologists and cardiac surgeons to refine their approach to female patients and thus improve outcomes. The book reflects the increasing awareness of gender differences with regard to coronary artery disease and structural valve heart disease. Examples include myocardial infarction, which carries a worse prognosis in women in part because they suffer from this disease mostly in the 7th decade of life, present more frequently with hemodynamic instability and later from symptom onset, and have fragile, small and tortuous coronary arteries that are more technically demanding in the context of primary percutaneous coronary intervention. Another example is symptomatic aortic stenosis, which carries a better prognosis in women who undergo trans-catheter aortic valve implantation partially due to a better annulus-prosthesis match, which leads to less residual paravalvular regurgitation, better left ventricular function and lower aggregation of comorbidities. Further, in women left ventricular response to aortic stenosis is typified by muscle hypertrophy with a small ventricular cavity. These differences are reflected in the clinical manifestations and their impact on diagnosis, treatment, and choice of tools and devices for use in interventional procedures. By explaining the at times subtle variances in disease and treatment techniques for female and male patients, this book will help practitioners select the most appropriate procedures and materials in a range of settings.

Chronic venous disorders are a major health problem due to their wide prevalence and socio-economic considerations. This book is a comprehensive manual providing state- of- the- art information on the diagnosis and management of these common problems. Till recently venous disorders have been getting secondary attention as compared to their arterial counterpart. However, the last two decades witnessed major technological advancements and therapeutic strategies for these problems. Written with a surgical perspective, this monograph covers the latest developments and recommended procedures in an easy-to-read format guiding the surgeon to prepare a rational treatment plan. Supplemented with numerous figures and illustrations, the chapters update the readers with how to evaluate such patients in their practices, selection criteria for appropriate procedures and how to manage the complications. The book includes basics of venous disorders, primary varicose veins and recurrence after surgery, chronic venous insufficiency, venous ulcers and congenital venous malformations. Detailed coverage of endo-venous procedures such as radio-frequency ablation, laser ablation and foam sclerotherapy are additional essential features of this book. Primarily intended for the practicing general surgeon, this volume is also relevant for residents in general surgery and vascular surgery.

This text provides a comprehensive, state-of-the art review of complex endovascular aortic techniques. It will serve as a valuable resource for vascular and cardiovascular surgeons, interventionalists, cardiologists, clinicians, bioengineers and researchers with an interest in complex aortic diseases. The book reviews imaging modalities, diagnostic work up and novel endovascular approaches. Technical aspects are provided by experts in the field, with over 600 illustrations and photographs of key steps for each type of procedure. Results of epidemiologic studies and national databases are summarized, as well as large institutional experiences. An evidence-based approach is used for recommendations regarding best therapies. Other highlights of this unique text include: A new, state-of-the-art review on fenestrated, branched and parallel stent-graft techniques from procedure planning to stent design and implantation. A text dedicated to a topic that has been increasingly recognized by vascular specialists as a priority area in aortic management. An updated overview of current designs and future developments. Special attention to technical details of the procedures with use of illustrations. Technical tips on how to get out of problems during these challenging procedures. Endovascular Aortic Repair: Current Techniques with Fenestrated, Branched and Parallel Stent-Grafts will serve as a very useful resource for physicians and researchers dealing with and interested in complex aortic diseases. It will provide a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up to date scientific and clinical information.

In the last years, indications for defibrillators and cardiac resynchronization therapy have expanded enormously; for this reason, and also due to the extension of human life length, the number of patients with implanted cardiac devices have steadily increased. The leads implanted for the functioning of these devices, however, have a limited duration in time and more and more their extraction will be a frequent issue in clinical practice, in order to treat short- and long-term complications, such as infections and failures.

Aim of this book is to provide readers with a state-of-the-art on lead extraction techniques. The chapters deal with leads characteristics, indications to lead removal, patient preparation, tools and techniques for extraction, and prevention and management of complications. In addition, a series of tips and tricks on how to treat some particular conditions (tight cost-clavicular space, fractured leads, ICD leads, dangered leads etc.), are given. A new extracting technique, according to which the extraction is performed through the internal jugular vein is described; several examples are included and many figures provide a thorough depiction of this innovative procedure.

The volume will be an excellent resource for all those involved in the management of cardiac patients: cardiologists, arrhythmologists, cardiac surgeons, GPs, pediatricians, and post-graduate students in these disciplines."

The thoraco-abdominal aortic pathology is not uncommon and represents the ultimate challenge for vascular surgeons. The book deals with the newest endovascular and hybrid approaches, together with more traditional surgical strategies. Written by internationally renowned experts in vascular and cardiac surgery, anesthesiology and radiology, the volume provides a very practical approach to the main problems encountered from diagnosis to postoperative care: general principles of aortic diseases, imaging techniques, surgical and anesthesiologic strategies and techniques and other specific problems are some of the topic dealt with. Numerous pictures illustrate the most important diagnostic findings and depict key techniques and strategies. Vascular and cardiac surgeons, anesthesiologists, perfusionists and radiologists will find in this volume useful and updated information for the treatment of this very challenging condition.

This book represents an up-to-date overview of reconstructive lymphovascular surgery, with coverage of all aspects from the bench to the bedside. After careful consideration of the pathophysiological and experimental basis for the described procedures, concise guidance is provided in the treatment of various conditions. Surgical technique is explained for the important indication of lymphedema of the upper and lower limbs due to localized blockage of the lymphatic system. Further important indications for which the surgical procedure is fully described include lymphoceles and lymph fistulas. Means of verifying results, especially important in the case of newer techniques, are discussed and the results obtained with the different techniques are extensively presented. The book will be an informative and instructive guide to current possibilities of reconstructive lymph vascular surgery and for interested readers in the fields of angiology, dermatology, gynecology, oncology, phlebology, physiotherapy, and surgery.

This is the first comprehensive book about surgery on and around the vertebral artery all along its cervical and intracranial course. This vessel has been considered for long as out of surgical reach leaving many different pathologies not or incompletely treated. The surgical exposure and control of the vertebral artery not only permit to treat lesions of the vertebral artery wall or developed in contact to it but also to improve the access to the intervertebral foramen (tumors, osteophytes), to the anterior aspect of the spinal cord (tumors, spondylotic spurs), to the foramen magnum and to the jugular foramen. This book written by leading experts includes all aspects of vertebral artery surgery from anatomy to imaging, surgical techniques and pathologies; it is illustrated by many figures especially operative views and schematic drawings so that the beginner as well as the experienced surgeon find useful information. One of the editors of this book (B. GEORGE) was recently awarded the Olivecrona award for his work on the surgery of the vertebral artery.

Microsurgical techniques are widely used in the field of orthopaedics. This book addresses all aspects of orthopaedic microsurgery, from development of the principles to their applications. Replantation of fingers, hands and extremity parts are well summarized by highly experienced microsurgical surgeons. The methods for tissue transplantation and microsurgical reconstruction of tissue defects, which have been proved to be successful tools for saving severely injured extremities, were developed by experienced orthopaedic surgeons in cooperation with plastic surgeons. Injuries to peripheral nerves and the brachial plexus are also discussed extensively in this monograph. All illustrations and tables were meticulously selected and are easy to understand. The book was written for all microsurgeons who work in the fields of orthopaedics, plastic and hand surgery. Guoxian Pei is a professor at the Department of Orthopaedics, Xijing Hospital, the Fourth Military Medical University, Xi An, China.

This book provides a systematic description of fundamental knowledge, application methods, and management issues about the clinical application of endovascular surgery and device. It is organized as the three parts. Part 1 introduces the development background of endovascular device and its knowledge hierarchy, and gives an overview on classification, structure, shape, and characteristics of the above device. Part 2 is based on a large number of clinical practices. It firstly summarizes the basic operation skills and conventional methods of endovascular device, and then exemplifies the application scheme of special device for complex cases. Part 3 discusses the management theory and methods of endovascular device in clinical application, puts forward the agile supply chain management model and autonomous intelligent decision-making method of device supply and cooperation management for clinical surgery, and designs its managerial system and guides. This book provides comprehensive and professional knowledge, advanced theory, and referential methods for clinical application and management of endovascular surgery and device. It is a useful guide for the clinical practice in specialized study and professional training in endovascular surgery, and provides the methods of neuro-management and smart medical service for patients.

Current Vascular Surgery: Northwestern Vascular Symposium is an annual publication that addresses contemporary topics and controversies in vascular and endovascular surgery, providing a comprehensive overview of the field's recent evolution. This volume is the result of the 41st Annual Vascular Symposium sponsored by the Division of Vascular Surgery, Feinberg School of Medicine, Northwestern University and held in Chicago on 8-10 December, 2016. The contributing authors were selected on the basis of recent peer-reviewed publications and national societal presentations; all are recognized leaders in their disciplines. This volume provides a comprehensive analysis of the current management of vascular disease as it relates to treatment of extracranial cerebrovascular and supra-aortic trunk disease, new approaches to lower extremity arterial and venous problems, and recent cutting-edge developments in open and endovascular approaches to treat aortic and visceral arterial disease, as well as novel techniques for hemodialysis access, complex venous problems, and upper extremity disorders. Each chapter has as its basis a presentation at the 41st Annual Vascular Symposium, but includes more in-depth details than is possible in a symposium presentation. Fifty-two chapters in ten sections covering the full range of vascular surgery. Clinical "pearls" from internationally-recognised experts. Includes perspectives on the history and evolution of the field.

This textbook focuses on the vascular biology and physiology that underlie vascular disorders in clinical medicine. Vascular biomedicine is a rapidly growing field as new molecular mechanisms of vascular health and disease are unraveled. Many of the major cardiovascular diseases including coronary artery disease, heart failure, stroke and vascular dementia are diseases of the vasculature. In addition vascular injury underpins conditions like kidney failure and cardiovascular complications of diabetes. This field is truly multidisciplinary involving scientists in many domains such as molecular and vascular biology, cardiovascular physiology and pharmacology and immunology and inflammation. Clinically, specialists across multiple disciplines are involved in the management of patients with vascular disorders, including cardiologists, nephrologists, endocrinologists, neurologists and vascular surgeons. This book covers a wide range of topics and provides an overview of the discipline of vascular biomedicine without aiming at in-depth reviews, but rather offering up-to-date knowledge organized in concise and structured chapters, with key points and pertinent references. The structure of the content provides an integrative and translational approach from basic science (e.g. stem cells) to clinical medicine (e.g. cardiovascular disease). The content of this book is targeted to those who are new in the field of vascular biology and vascular medicine and is ideal for medical students, graduate and postgraduate students, clinical fellows and academic clinicians with an interest in the vascular biology and physiology of cardiovascular disease and related pathologies.

This book provides a systematic description of fundamental knowledge, application methods, and management issues about the clinical application of endovascular surgery and device. It is organized as the three parts. Part 1 introduces the development background of endovascular device and its knowledge hierarchy, and gives an overview on classification, structure, shape, and characteristics of the above device. Part 2 is based on a large number of clinical practices. It firstly summarizes the basic operation skills and conventional methods of endovascular device, and then exemplifies the application scheme of special device for complex cases. Part 3 discusses the management theory and methods of endovascular device in clinical application, puts forward the agile supply chain management model and autonomous intelligent decision-making method of device supply and cooperation management for clinical surgery, and designs its managerial system and guides. This book provides comprehensive and professional knowledge, advanced theory, and referential methods for clinical application and management of endovascular surgery and device. It is a useful guide for the clinical practice in specialized study and professional training in endovascular surgery, and provides the methods of neuro-management and smart medical service for patients.

The Oxford Textbook of Vascular Surgery draws on the expertise of over 130 specialist contributors to encompass the field of vascular surgery. Through the use of figures, findings of contemporary trials, and additional online content, this textbook is an excellent study material for surgical trainees entering their final two years of training, in addition to serving as an effective reference source for practicing surgeons. This volume discusses the epidemiology, vascular biology, clinical features and management of diseases that affect the vasculature and contains dedicated chapters which address topics such as paediatric surgery, damage control surgery, and amputations. The text follows a logical framework which complements the published Intercollegiate Surgery Curriculum making it particularly useful in preparation for the Intercollegiate Examination. The online version of The Oxford Textbook of Vascular Surgery is free for twelve months to individual purchasers of this book and contains the full text of the print edition, links to external sources and informative videos demonstrating current surgical techniques, making this a valuable resource for practicing surgeons. The field of vascular surgery has advanced rapidly in recent years and has expanded to include the techniques of interventional radiology and cardiology which are also extensively covered in this volume, making it an authoritative modern text. By combining contemporary evidence-based knowledge with informative figures, online resources and links to the current training curriculum, The Oxford Textbook of Vascular Surgery is a highly valuable source of information and will become the standard reference text for all who study vascular disease and its treatment.

Developed for the International Association for Trauma Surgery and Intensive Care (IATSIC), the Manual of Definitive Surgical Trauma Care 5e is ideal for training all surgeons who encounter major surgical trauma on an infrequent basis. This new edition includes both an e-version, and also a microSD card containing over 20 operative videos. The increasing role of non-operative management (NOM) has been recognised, and the Military Module is substantially updated to reflect recent conflict experience. An expanded section highlights trauma management under austere conditions.Written by faculty who teach the DSTC Course, this definitive and well established book focuses on life-saving surgical techniques to use in challenging and unfamiliar incidents of trauma.

Providing a practical, current, evidence-based approach to all aspects of perioperative care for the patient with vascular disease, Vascular Anaesthesia is an essential read for all vascular anaesthetists, anaesthetic nurses and anyone else involved in the care of vascular patients throughout the world. Vascular Anaesthesia summarizes current knowledge, particularly on interventional procedures (radiological, diagnostic, and surgical). This book also equips the trainee anaesthetist with the scientific and clinical knowledge to pass the Final FRCA examination. It enables doctors to approach vascular surgical patients with a firm understanding of a particular procedure, particularly its risks and options for perioperative management based on current best practice. The management of the patient with vascular disease is evolving rapidly: this indispensible poket reference is of sufficient detail to update the regular and occasional vascular anaesthetist with current best practice for particular, common clinical scenarios. The book also equips the non-anaesthetic medical, nursing, and theatre staff with knowledge and understanding of all other aspects of perioperative care.

Challenging Concepts in Interventional Radiology is a cased based guide to the most challenging aspects of interventional radiology and endovascular procedures. The 31 Cases have been selected to cover a wide-spectrum of scenarios, from the endovascular repair of thoracic and abdominal aortic aneurysms to the ablation of lung and kidney tumours. Cases are examined from a multidisciplinary approach with consideration of diagnosis, practical procedures, evidence base, and guidelines. Case commentaries from renowned experts in the field provide a useful and high level narrative across each case and compliment the clinical tips and evidence provided throughout. The collaboration of authorship between trainees and experts provides a unique insight into the management of the most complex and important cases in the radiology field. With a highly user friendly format, the textbook provides clinical tips and expert commentary for easy use in every day clinical practice. Suitable for candidates for the European Board of Interventional Radiology exam, fellows of Interventional Radiology, British Society of Endovascular Therapy fellows and radiologists, Challenging Concepts in Interventional Radiology appeals to a wide-ranging level of radiologists.

With an invaluable selection of color images, this guide authoritatively covers the identification, assessment, pathophysiology, epidemiology, and treatment of disorders affecting the venous and lymphatic anatomy. Written by experts from several fields, this source considers topics including the management of deep venous thrombosis, chronic venous insufficiency, venous trauma, and surgical and pharmacologic therapies for these conditions.

Chronic Venous Insufficiency, the first volume in the Contemporary Endovascular Management book series, presents a current, succinct review of the rapidly evolving field of venous disease. In recognition of the significant effects of venous disease on patients and the quickly changing modes of therapy in the field, this volume fulfills the need for a comprehensive assessment of the treatment paradigms and innovative techniques now available. Volume 1 examines varicose veins, chronic venous reconstructions, and arteriovenous malformations from initial presentation through imaging and diagnosis to general and advanced therapies. As leaders in their field, the authors of Chronic Venous Insufficiency focus their contributions on current and relevant research and facts, specifically aiming to close knowledge gaps as well as to provide essential information for the practicing physician, the trainee, and the midlevel provider. Audiences for Chronic Venous Insufficiency: Vascular surgeons Phlebologists Vascular surgery residents and fellows Interventional radiologists General surgeons with interest in veins Cardiologists (peripheral vascular practice) Series Description: The Contemporary Endovascular Management series is designed to be a focused, relevant, and timely review of the modern aspects of imaging and intervention in specific vascular beds. Each volume in the series addresses one vascular bed and equips readers with the current information necessary for vascular practice using a clear and easy-to-access format. Audiences for Contemporary Endovascular Management series: Vascular surgeons Cardiologists (peripheral vascular practice) Interventional radiologists Invasive nephrologists and neurologists

This book discusses geometric and mathematical models that can be used to study fluid and structural mechanics in the cardiovascular system. Where traditional research methodologies in the human cardiovascular system are challenging due to its invasive nature, several recent advances in medical imaging and computational fluid and solid mechanics modelling now provide new and exciting research opportunities. This emerging field of study is multi-disciplinary, involving numerical methods, computational science, fluid and structural mechanics, and biomedical engineering. Certainly any new student or researcher in this field may feel overwhelmed by the wide range of disciplines that need to be understood. This unique book is one of the first to bring together knowledge from multiple disciplines, providing a starting point to each of the individual disciplines involved, attempting to ease the steep learning curve. This book presents elementary knowledge on the physiology of the cardiovascular system; basic knowledge and techniques on reconstructing geometric models from medical imaging; mathematics that describe fluid and structural mechanics, and corresponding numerical/computational methods to solve its equations and problems. Many practical examples and case studies are presented to reinforce best practice guidelines for setting high quality computational models and simulations. These examples contain a large number of images for visualization, to explain cardiovascular physiological functions and disease. The reader is then exposed to some of the latest research activities through a summary of breakthrough research models, findings, and techniques. The book's approach is aimed at students and researchers entering this field from engineering, applied mathematics, biotechnology or medicine, wishing to engage in this emerging and exciting field of computational hemodynamics modelling.

This concise, easy-to-use book offers expert insights into current controversies in vascular neurosurgery with a view to providing the practitioner with authoritative practical guidance that will assist in the management of difficult disease entities. While vascular neurosurgery has undergone unprecedented advances during the past decade, enabling safer and easier access to previously untreatable pathology, this progress has been accompanied by confusion as to what constitutes best, or even acceptable, practice. Here, experts in the field discuss the various tools available and explain how best to use them when confronted by different pathologies, drawing upon their personal experience. Each chapter focuses on a specific case that is discussed by two experienced surgeons; a third author then evaluates the case, highlighting the available evidence and pearls in the treatment of that particular disease. The authors have been carefully chosen to provide a truly balanced viewpoint on paradigms that they themselves use. They therefore have a sound understanding of the thought processes of surgeons when dealing with challenging diseases for which there may be no single correct path. Furthermore, they are well placed to identify not only appropriate uses of new treatment options and technologies but also circumstances in which their use is best avoided. The ultimate benefactor of this book will be the patient: our biases as physicians should never become a patient's morbidity.