In this concise but authoritative book, the authors take the reader through the epidemiology, risk factors and the basic mechanism of coronary artery disease. In addition, they explain how coronary microvascular dysfunction can lead to angina, even after successful angioplasty following a heart attack. The methods for diagnosis and the options for treatment are explained, ending with a discussion of the evolution of coronary angioplasty from balloon catheters to novel, fully resorbable polymeric drug eluting stents. Enclosed is a list of currently available commercial devices, as well as a listing of experimental products under research and development, so that readers can appreciate the serious nature of this disease and have an understanding of how the medical device sector is attempting to address this major healthcare problem. Globally in 2010, ischemic heart disease was the cause of 13.3% of all deaths. In the US alone, the direct medical costs from coronary artery disease and stroke are currently estimated to be $126 billion per year, and are expected to rise to $309 billion by 2035.

Following the success of its last symposium and book entitled 'The Evidence for Vascular Surgery', the Joint Vascular Research Group (JVRG) brings you this book. The book describes recent developments and best practice in vascular surgery, with an emphasis on multi-disciplinary care pathways. It is based upon a symposium held in Sheffield in June 2002 that aimed to improve the provision and equality of care for patients with peripheral arterial and venous disease. Many members of the JVRG have contributed to this book, including vascular surgeons, anaesthetists, radiologists, nurses and vascular technologists. The book consists of five sections covering the main areas of management of patients with peripheral vascular disease: Outpatients and medical management; Vascular imaging and endovascular intervention; Vascular surgery; Anaesthesia and theatres; Organisational aspects of care.

This book answers frequently asked questions about common pediatric neurosurgical conditions related to vascular malformations of the brain and spinal cord, in an attempt to fill in the gap and answer numerous questions that arises after a diagnosis is made. Pediatric patients with neurosurgical conditions are almost always referred from either primary care physicians, neurologists internists or a specialist in family medicine. Recently, neurosurgeons treating adult population also refer a pediatric patient to their colleague specialized in this field. There are over 1500 academic and private hospitals in the US who have dedicated tertiary Neurosurgery services and cater thousands of small children every year, in addition to numerous centers that have level 1 and 2 trauma care. However, there are few tertiary level Pediatric centers which can provide quality care for neurosurgical conditions. This book is specially written and illustrated for residents, fellows and consultants/attendings in all pediatric related specialties, including but not limited to Neurosurgery, Neurology, Pediatrics, Radiology, Anesthesia.

This book reviews the natural course of arteriovenous malformation (AVM) disease and the active treatment modalities. These are compared with surgical and neuropsychological results achieved at the Military University Hospital, Prague, Czech Republic. Based on these comparisons, treatment recommendation for AVM is articulated. Furthermore, the long-term efficacy of different treatment is discussed. This book is written by an international group of European authors, and is aimed at neurovascular surgeons and neurosurgical residents.

Vascular and Endovascular Surgery meets the needs of surgeons in higher training and practising consultants for a contemporary and evidence-based account of this sub-specialty that is relevant to their general surgical practice. It is a practical reference source incorporating the most current information on recent developments, management issues and operative procedures. The text is thoroughly referenced and supported by evidence-based recommendations wherever possible, distinguishing between strong evidence to support a conclusion, and evidence suggesting that a recommendation can be reached on the balance of probabilities. For this Sixth Edition the authorship team across the series has been expanded to include additional European and World experts, with an increased emphasis on global practice. Throughout all six volumes the contents have been extensively revised in line with recently published evidence. Detailed supportive key references are provided and are also included within the comprehensive list of references in the accompanying ebook. Links to recommended online videos have been added where appropriate. The Companion to Specialist Surgical Practice series provides a current and concise summary of the key topics within the major sub-specialties of general surgery. Each volume highlights evidence-based practice both in the text and within the extensive list of references at the end of every chapter. Vascular surgery is developing at a rapid pace, especially in the field of medical therapy and endovascular interventions. This new edition aims to put these developments into context, and give a balanced view with regard to technological advances and more traditional techniques. Vascular and endovascular practitioners will find this a very useful resource in their day to day clinical practice.

This book presents the amalgamation of topics to make you interested for leisure reading, for an outstanding clinician. These topics go beyond the basic teachings; presenting bits of medical knowledge that can help prevent diagnostic delays and face therapeutic challenges. This book will provide interesting information to a better understanding and management of vascular diseases.

This text provides a comprehensive, state-of-the-art review of catheter based approaches to valve and aortic diseases. The scope encompasses involve all the current and upcoming transcatheter aortic valve technologies as well as mitral, pulmonary and tricuspid valve technologies. Aortic diseases including transcatheter repair of descending aneurysms are included and the upcoming technologies designed to repair aortic dissections, traumatic injury, and ascending arch stent repair are highlighted. Catheter Based Valve and Aortic Surgery will be a useful tool for cardiac and vascular surgeons, interventional cardiologists, general cardiologists, and clinicians and researchers with an interest in these exciting new developments in structural heart and vascular diseases.

Die "Gefasschirurgie" aus der renommierten Kirschnerschen Operationslehre - jetzt als Sonderausgabe. - Umfassend: Die gesamte Bandbreite der klassischen, konventionellen Gefasschirurgie - Unubertroffen anschaulich: UEber 600 erstklassige Abbildungen, viele davon als farbige Bilderfolgen zu den Operationsverfahren - Mit einem Vorwort von Prof. van Dongen zum aktuellen Stellenwert der beschriebenen Therapien Ein Klassiker von zeitlosem Wert - auch fur das 21. Jahrhundert!

Highly visual and packed with useful, practical information, Atlas of Endovascular Venous Surgery, 2nd Edition, provides real-world instruction on the evaluation, diagnostic imaging, and medical and endovascular surgical management of acute and chronic venous diseases. Dr. Jose Almeida, pioneering expert in the field and host of the annual International Vein Congress, along with other highly regarded practitioners, offers an authoritative understanding of what causes increased venous pressure and solutions for reducing venous hypertension. Detailed, full-color intraoperative illustrations capture key teaching moments, helping you better understand the nuances of surgery and improve your ability to perform cutting-edge procedures. Uses full-color line art to depict key anatomic features and anatomic approaches to venous surgeries, providing you with an overview of the relevant clinical anatomy for each procedure. Shows the correlation between radiologic appearance (ultrasound, CT, MRI) and anatomic and surgical views. Accompanies each surgical procedure with concise, descriptive text, giving you a step-by-step "walk through" of each technique. High-quality intraoperative videos demonstrate key stages of intraoperative technique. Ideal for all practitioners who treat patients with venous disorders, including vascular and general surgeons as well as interventional radiologists. Reflects the many developments that have taken place in the treatment of the deep venous system, especially the use of new anticoagulants and techniques to treat the sequelae of acute and chronic venous thromboembolic disease. Includes five brand-new chapters covering venous hemodynamics; new concepts in the management of pulmonary embolus; endothermal heat induced thrombosis; deep venous incompetence and valve repair; and nutcracker syndrome. Features significant updates throughout, including new devices in the management of thromboembolic disease; aggressive techniques for recanalizing iliofemoral venous occlusions, new nomenclature and endovascular approach to the treatment of pelvic venous disorders, new non-thermal devices for saphenous vein ablation, new stents for treatment of iliac vein obstruction and new devices for clot management, and endovascular and open repair of deep vein obstruction and reflux. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

This volume explores the latest techniques used to study the field of tissue engineered vascular grafts (TEVGs). The chapters in this book cover a wide array of topics such as deriving vascular cells from monocytes and induced pluripotent stem cells; engineering vascular grafts using various biomaterials and stem cells, stem cell-derived, or primary vascular cells; biomaterial modification by anticoagulation molecules; vascular bioengineering technologies such as 3D bioprinting; and fabrication of TEVGs with different geometry and multiphase structures. This book also features protocols for grafting and evaluation of vascular grafts in animal models, vascular imaging in animals, and the quantification of blood vessel permeability. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Vascular Tissue Engineering: Methods and Protocols is a valuable resource for biomedical engineers, cell biologists, vascular surgeons, doctors, and nurses.

In this era of evidence-based medicine, clinicians treat common conditions according to guidelines and protocols derived from the results of randomised clinical trials. This book will help vascular specialists when they have to treat a patient with an unusual condition where they may have no experience and there is little published scientific information. The Joint Vascular Research Group has collected rare vascular conditions in a register for over a decade, and this book reviews the experience, together with the best information from the surgical literature. The authors give a practical guide on the diagnosis and management of rare vascular disorders. This book should be read by everyone who manages patients with vascular disease.

Peripheral Artery Disease is a circulatory condition usually caused by the buildup of fatty deposits and calcium in the walls of the arteries. The condition is often painful and chronic but can be managed with lifestyle changes and medication. Chapter One describes the psychological factors associated with peripheral arterial disease. Chapter Two describes how lifestyle changes play an important role in the management of diabetes and peripheral artery disease. Chapter Three explains the role of the family physician in risk management of peripheral artery disease. Lastly, Chapter Four focuses on questionnaires for primary care physicians, which can be used for peripheral arterial disease symptom screening and assessing functional impairment and quality of life of patients.

Endovascular neurosurgery is now the most practiced therapeutic approach for most vascular lesions involving the brain and spinal cord. At the beginning, balloons were the only available technique; later coils, embolic agents, and stents are introduced. With the expansion of endovascular devices and techniques, the treatment strategies for cerebrospinal vascular diseases have been refined. Neurosurgeons must have the mindset to embrace and nurture progress and technological advances. The pioneers of endovascular neurosurgery considered the impossible and tenaciously stood by their dreams. Their revolutionary ideas and inventions truly reflected their courage, faith, and determination. The shift away from open surgical approaches has had far-reaching implications for how we train neurosurgical residents and fellows and how we certify these individuals once their training is completed. With the maturity of endovascular neurosurgery technology, we need to give the resident and fellow training for neurovascular surgery. This book describes the endovascular diagnosis and treatment of vascular lesions involving the brain and spinal cord using catheters in the DSA (digital subtraction angiography) unite. The field of endovascular neurosurgery has resulted in effective endovascular therapies for carotid-cavernous fistulas(CCFs), intracranial aneurysms, arteriovenous malformations (AVMs), dural arteriovenous fistulas, atherosclerosis of cerebral arteries, acute stroke, carotid artery disease, and vascular tumours of the head, neck, and spinal vascular malformations and tumours. The scope of practice of neurovascular endovascular surgery has become complex, requiring training in specific skill sets and techniques. The evolution of the neuroendovascular field has resulted in the development of program requirements for residency or fellowship education in endovascular neurosurgery.

Vascular diseases are the leading cause of death worldwide. Distinguished clinical and surgical approaches have attempted to overcome its morbidity and mortality; still 17.9 million people die every year due to vascular affections. Stem cell therapy has emerged as a promising therapeutic strategy. Stem cells synthesize and secrete cytokines that promote cell recruitment, immunomodulation, extracellular matrix remodeling, angiogenesis, and neuroregeneration, all of which promote regeneration. Besides that, stem cells are also capable of differentiating in various cell types, being employed in tissue engineering. Preclinical and clinical investigations have reported efficacy of stem cell therapy for various vascular diseases. Even though results are encouraging, the studies demonstrate variation in stem cell type and origin, route and protocol for administration, and concomitant use of other treatment strategies, impairing easy interpretation of results and clinical application. The purpose of this book is to compile and comprise the current state of the evidence regarding stem cell therapy for each vascular disease, elucidating possible clinical applications. More than an objective guide for readers on the use of this novel treatment strategy, this publication will advocate for stem cell therapy use and development and will be of significant interest to physicians in a wide range of disciplines as well as researchers.

This volume explores the latest techniques used to study the field of tissue engineered vascular grafts (TEVGs). The chapters in this book cover a wide array of topics such as deriving vascular cells from monocytes and induced pluripotent stem cells; engineering vascular grafts using various biomaterials and stem cells, stem cell-derived, or primary vascular cells; biomaterial modification by anticoagulation molecules; vascular bioengineering technologies such as 3D bioprinting; and fabrication of TEVGs with different geometry and multiphase structures. This book also features protocols for grafting and evaluation of vascular grafts in animal models, vascular imaging in animals, and the quantification of blood vessel permeability. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Vascular Tissue Engineering: Methods and Protocols is a valuable resource for biomedical engineers, cell biologists, vascular surgeons, doctors, and nurses.

This book presents a comprehensive and state-of the-art approach to vascular disease for the geriatric patient, focusing on vascular pathology and interventions but also on perioperative care, anesthetic care, functional outcomes and quality of life, as well as ethical considerations that impact decision making. The book addresses open and endovascular interventions in different vascular beds, as well as preoperative workup and optimization, anesthetic considerations, all aspects and expectations of the postoperative care and recovery and is the only book to include specialize in the intricacies of the care of the geriatric patients, the challenging recovery and neurocognitive changes, and ethical considerations for the end stage geriatric patient or in the setting of postoperative complications. Written by experts in the field, each section addresses patient selection, pre-operative considerations, technical conduct of the most common operations with open or endovascular options, and avoiding complications. A brief review of the existing literature addressing the particular topic follows in each section. With its concise yet comprehensive summary of the field, Vascular Disease in Older Adults is the ultimate resource for geriatricians, cardiologists, surgeons, anesthesiologists, and all physicians of who care for the aging patient with vascular disease.