The last five years have witnessed an increasing interest in the subject of transmyocardial laser revascularization (TMR) as illustrated by the number of abstracts presented at the meetings of the American Heart Association and the American College of Cardiology (Figure). The ideas and concepts associated with this particular method of myocardial revascularization have changed dramatically over even this short period of time. The original premise of "de-evolving" mammalian hearts to recreate a reptilian-like myocardial circulation by making multiple channels through the myocardium has been almost (but perhaps not quite) completely dismissed. Now, the most popular notion is that there is an angiogenic response to myocardial channel making. It is this development of new blood vessels that is thought to be responsible for the apparent improvements in symptoms and blood flow. Along the way, the idea that a channel could stay open and allow blood to flow directly from the ventricular chamber has found little support. Rather than directly explore all of these issues and merely duplicate previously published articles, our aim was to take a novel approach: that is, to step back from these arguments and provide perspective from the vantage point of distance. In the case of trans myocardial revascularization, distance comes both in terms of history and in terms of methodology and knowledge from other fields of research. Historically, innovative methods of myocardial revascularization are by no means uncommon. The first two chapters deal with this historical' perspective.

This book represents the first comprehensive textbook devoted to the standard of care, current guidelines and innovations in the field of mesenteric vascular disease. The book reviews imaging modalities, diagnostic work up, physiologic tests, traditional open surgical techniques and novel endovascular approaches. Technical aspects of both open surgical and endovascular techniques are provided by experts in the field, with illustrations and photographs of key steps for each type of procedure. Results of epidemiologic studies and national databases are summarized, as well as large institutional experiences. An evidence-based approach is used for recommendations regarding best therapies. Diagnostic approaches including imaging and novel physiologic tests, including gastric tonometry and oxygen light spectroscopy are covered. Mesenteric Vascular Disease: Current Therapy will serve as a very useful resource for clinicians, surgeons, interventionalists, gastroenterologists and researchers dealing with and interested in mesenteric vascular diseases.

Examining the history of arterial repair, Of Life and Limb investigates the process of surgical innovation by exploring the social, technological, institutional, and martial dynamics shaping the introduction and adoption ofa new operation. In 1880, patients suffering from vascular disease faced amputation -- or death. By 1960, a suite of revolutionary techniques and technologies empowered surgeons to remedy aneurysms, mend damaged vessels, and treat arteries cloggedwith cholesterol, saving the lives and limbs of patients around the world. Tracking this remarkable transformation, Of Life and Limb: Surgical Repair of the Arteries in War and Peace, 1880-1960 reveals how social, technological, institutional, and military dynamics interplay to catalyze modern surgical innovation. Author Justin Barr examines each of these phenomena through the complementary perspectives of academic historian andclinical surgeon, marshaling extensive research and incisive analysis into a broadly applicable model that helps frame, illuminate, and forecast change in surgery. Justin Barr received his PhD in History from Yale University and his MD from the University of Virginia. He is currently in residency for general surgery at Duke University.

Percutaneous cardiac and endovascular procedures performed by a variety of interventional physicians continue to evolve and expand. One of the most important steps in performing these procedures is vascular access and their Achilles heel is vascular access site complications. This volume is here to help the clinician, providing a practical overview of the techniques and technologies used in top catheterization laboratories to access the arterial and venous beds. Dr. Mazen Abu-Fadel and his contributors, part of the renowned cardiovascular team at the University of Oklahoma College of Medicine, carefully walk the reader through the various techniques used to obtain vascular access into most arterial and venous sites. They thoroughly describe current data, techniques, advantages, risks, and benefits of each vascular access site. Covering everything from anatomic landmarks to closures devices, Arterial and Venous Access in the Cardiac Catheterization Lab offers a complete overview of each procedure. In addition, it provides an up-to-date guide to the best medical technologies and equipment used when performing these procedures. Arterial and Venous Access in the Cardiac Catheterization Lab is an invaluable resource for a wide range of clinical personnel, from attending physicians and trainees to nursing staff and vascular technicians. Written by experienced leaders in the field, it demonstrates how to perform complex, risky procedures while providing patients with expert care.

This book is a comprehensive guide to the latest advances and techniques in vascular and endovascular surgery. Divided into nineteen chapters, the book begins with discussion on translational vascular research, new oral anticoagulants, and statins. The following sections provide detailed explanations of both common and more complex surgical procedures used in the treatment of vascular disorders and diseases. Highly illustrated with nearly 200 clinical images and tables, the book presents the experiences of vascular specialists worldwide. Key Points Comprehensive guide to the latest advances and techniques in vascular and endovascular surgery Covers both common and more complex surgical procedures Includes discussion on translational vascular research, new oral anticoagulants, and statins Highly illustrated with nearly 200 clinical images and tables

This publication is intended as a guide to common diagnostic, operative and percutaneous techniques used in creating and maintaining vascular access for hemodialysis. When writing the text, the authors have focused on surgeons in training, fellows, interventional radiologists and clinically active nephrologists. Dialysis nurses and other clinicians involved in the care of end stage renal disease and dialysis patients will also greatly benefit from this handbook. This 2nd edition of the text contains expanded sections on ESRD, access surveillance and surgical and diagnostic devices, as well as new sections on peritoneal and dual lumen catheter placement, commonly used drugs and dialysis, hemo- and peritoneal dialysis techniques and CPT and ICD coding for statistical and billing purposes. These changes reflect the highly technical nature of clinical management in this evolving specialty.

This book identifies the 50 key scientific articles in the field of vascular and endovascular surgery. It provides a commentary to each carefully selected paper and explains why these papers are so important, thus providing every surgeon with the foundation stones of knowledge in this fast-moving area. There has been an exponential increase in the volume and quality of published research relating to vascular and endovascular surgery in recent decades. Among thousands of articles, a small fraction is truly "game changing." Such studies form the foundations of vascular surgery today and the selection of papers within this book provide the 50 landmark papers every 21st-century vascular and endovascular surgeon needs to know. A valuable reference not only to the established surgeon, but also to vascular surgery residents and trainees, as well as to more experienced surgeons as they continue to learn new techniques and approaches and to improve their knowledge of vascular disorders and treatments. The papers provide an evidence-based resource for those surgeons preparing for professional exams and may inspire clinicians to produce new research. About the Editors Juan Carlos Jimenez MD, MBA Professor of Surgery Gonda (Goldschmied) Vascular Center David Geffen School of Medicine at UCLA Los Angeles, California Samuel Eric Wilson, MD Distinguished Professor of Surgery and Chair Emeritus University of California Irvine Irvine, California

Vascular care has evolved from conservative therapy and open surgical therapy to a minimally invasive approach using endovascular techniques, laparoscopic or thoracoscopic techniques as well as hybrids of open and endovascular techniques. This volume provides up-to-the-minute information and details new developments and procedures.

Now in its fourth edition, Vascular Ultrasound offers a compact yet comprehensive practical guide for anyone working in the field of vascular sonography. The book is written by expert practitioners as an easily accessible reference, providing key information suited to sonographers in their day-to-day practice. It covers essential vascular investigations undertaken by ultrasound departments and vascular laboratories in more detail than general ultrasound textbooks, but without overwhelming sonographers with highly complex information that may not be relevant to them. Here you will find essential information including the principle of ultrasound physics to enable accurate assessment of the peripheral circulation and blood flow, the use of the main scanner functions and controls, the main disorders of the arterial and venous circulation system with appropriate treatment and management, and techniques for the diagnosis and grading of disease. Practical and focused, with clear explanations. Step-by-step guide to scanning and obtaining optimal images. Extensive diagrams and figures to demonstrate key information with practical examples. Appendices and quick reference tables. Small and compact - easy to carry to studies, teaching sessions and clinics.

Endovascular Neurosurgery represents a unique collaboration between contributors from a number of specialties, all of whom are concerned with the management of cerebrovascular disease. This provides a balanced account of the efficacy of interventional endovascular techniques in this group of conditions. As a result, Endovascular Neurosurgery will prove an invaluable account of a relatively new specialty and will be essential reading for neurosurgeons, neurologists, neuroradiologists, neurophysiologists and neuroanaesthetists.

The field of vascular anomalies has grown rapidly in last 25 years. Molecular genetics has led to discovery of genes that cause vascular anomalies. Interventional radiology has become a major contributor to accurate diagnosis and management of previously untreatable disorders. New pharmacologic therapies are under investigation and surgical protocols have been established. Vascular Anomalies: Hemangiomas and Malformations is a comprehensive and interdisciplinary textbook ideal for dermatologists, interventional radiologists, surgical specialists, ophthalmologists, pathologists, geneticists, paediatricians, hematologic-oncologists, and vascular biologists. With a central motif of the biologic dichotomy of vascular tumors and vascular malformations, this book is organized into chapters which address clinical presentation, diagnostic imaging, molecular genetics, pathogenesis, histopathology, and management of vascular anomalies. Generous, full-colour images compliment this extensive volume written by three colleagues and their teammates from Children's Hospital Boston and Harvard Medical School, with leading specialists from other centers.

Advances in Phlebology and Venous Surgery Volume 1 contains chapters covering many of the most interesting areas of Phlebology. Chapters are all written by international experts in their own fields. Subjects covered include: endovenous thermoablation (Radiofrequency / Laser / Steam) non-thermal endovenous ablation (Glue / MOCA) discussion of LEED venous leg ulcers - due to superficial and deep venous disease transvaginal duplex ultrasound for the diagnosis of venous reflux pelvic veins - diagnosis and treatment for reflux and obstructive disease as well as other relevant subjects. This book will have something of interest for everyone who is interested in Phlebology and/or Venous Surgery. This book is produced by COP College of Phlebology and some of the contents were presented at the COP International Veins Meeting in London in March 2017. The College of Phlebology annual conference is held each March in London, UK.

This book presents a comprehensive and state-of the-art approach to vascular disease for the geriatric patient, focusing on vascular pathology and interventions but also on perioperative care, anesthetic care, functional outcomes and quality of life, as well as ethical considerations that impact decision making. The book addresses open and endovascular interventions in different vascular beds, as well as preoperative workup and optimization, anesthetic considerations, all aspects and expectations of the postoperative care and recovery and is the only book to include specialize in the intricacies of the care of the geriatric patients, the challenging recovery and neurocognitive changes, and ethical considerations for the end stage geriatric patient or in the setting of postoperative complications. Written by experts in the field, each section addresses patient selection, pre-operative considerations, technical conduct of the most common operations with open or endovascular options, and avoiding complications. A brief review of the existing literature addressing the particular topic follows in each section. With its concise yet comprehensive summary of the field, Vascular Disease in Older Adults is the ultimate resource for geriatricians, cardiologists, surgeons, anesthesiologists, and all physicians of who care for the aging patient with vascular disease.

Featuring up-to-date information on current topics in vascular surgery, the second edition of Postgraduate Vascular Surgery is aimed at surgical trainees to help them prepare for the FRCS intercollegiate and Board exams. With chapters written by experts in their respective fields, the book contains concise information on surgical procedures, diagnosis and management of vascular conditions. Each section includes bullet point summaries, relevant clinical trials, and references for further research, making it the ideal resource for study. This book will also help candidates preparing for the European and Australian board exams. Practicing surgeons will also find this title useful for updating their knowledge.

A highly pragmatic, high yield concise guide that is relatively easy to digest . It is heavily geared to actually doing the job of a day one vascular consultant, which is what the FRCS exam is all about. Written by a recently qualified vascular surgeon with a commitment to teaching.

Membrane Receptors, Channels and Transporters in Pulmonary Circulation is a proceeding of the 2008 Grover Conference (Lost Valley Ranch and Conference Center, Sedalia, Colorado; September 3-7, 2008), which provided a forum for experts in the fields of those receptors, channels and transporters that have been identified as playing key roles in the physiology and pathophysiology of the pulmonary circulation. The book rigorously addresses: i) recent advances in our knowledge of receptors, channels and transporters and their role in regulation of pulmonary vascular function; ii) how modulation of expression and function of receptors, channels and transporters and their interrelationships contribute to the pathogenesis of pulmonary vascular disease; and iii) the therapeutic opportunities that may be revealed by enhancing our understanding of this area. The overall goal was to explore the mechanisms by which specific receptors, channels and transporters contribute to pulmonary vascular function in both health and disease, and how this knowledge may lead to novel interventions in lung dysplasia, pulmonary edema, lung injury, and pulmonary and systemic hypertension to reduce and prevent death from lung disease. Membrane Receptors, Channels and Transporters in Pulmonary Circulation is divided into six parts. Part 1 (Ion Channels in the Pulmonary Vasculature: Basics and New Findings) is designated for basic knowledge and recent findings in the research field of ion channels in pulmonary circulation. There are five chapters in Part I discussing the function, expression, distribution and regulation of various ion channels present in pulmonary vascular smooth muscle cells and how these channels are integrated to regulate intracellular Ca2+ and cell functions. Part II (TRP Channels in the Pulmonary Vasculature: Basics and New Findings) is composed of five chapters that are exclusively designed to discuss the role of a recently identified family of cation channels, transient receptor potential (TRP) channels, in the regulation of pulmonary vascular tone and arterial structure. Part III (Pathogenic Role of Ion Channels in Pulmonary Vascular Disease) includes four chapters that discuss how abnormal function and expression of various ion channels contribute to changes in cell functions and the development of pulmonary hypertension. Part IV (Receptors and Signaling Cascades in Pulmonary Arterial Hypertension) consists of five chapters devoted to the role of bone morphogenetic protein receptors, Notch receptors, serotonin receptors, Rho kinase and vascular endothelial growth factor receptors in the development of pulmonary arterial hypertension. Part V (Receptors and Transporters: Role in Cell Function and Hypoxic Pulmonary Vasoconstriction) includes four chapters designed to illustrate the potential mechanisms involved in oxygen sensing and hypoxia-induced pulmonary vasoconstriction and hypertension. Part VI (Targeting Ion Channels and Membrane Receptors in Developing Novel Therapeutic Approaches for Pulmonary Vascular Disease) consists five chapters which discuss the translational research involving on membrane receptors, channels and transporters, including their potential as novel drug targets. We hope that Membrane Receptors, Channels and Transporters in Pulmonary Circulation will allow readers to foster new concepts and new collaborations and cooperations among investigators so as to further understand the role of receptors, channels and transporters in lung pathophysiology. The ultimate goal is to identify new mechanisms of disease, as well as new therapeutic targets for pulmonary vascular diseases. An additional outcome should be enhanced understanding of the role of these entities in systemic vascular pathophysiology, since the conference will include researchers and clinicians with interests in both pulmonary and systemic circulations.

This Vascular Surgery Atlas is a 'How to' book that allows the reader to focus on the technical aspects of the most commonly performed vascular procedures. The book is edited by two seasoned vascular surgeons with a well established experience in surgical education. The authors have been selected from both sides of the Atlantic to provide the expertise necessary to cover the various procedures.The atlas is focused on open surgical procedures and also covers essential endovascular procedures such as 'Endovascular Abdominal Aortic Aneurysm Repair and Carotid stenting.' It also includes a section on exposures of the infrainguinal vessels. The format allows the reader to easily follow the various steps of procedures. The art work shows all the details necessary to understand the anatomy and the technical aspects of the procedure. The layout of having text on one side and the associated art on the opposite page allows the reader to easily follow and understand the various steps on the described procedure.The atlas will benefit surgical residents, vascular surgery fellows and vascular surgeons.

This atlas provides all the basic and advanced information required by surgeons in order to understand fully the skull base anatomy. It is organized according to anatomo-surgical pathways to the hidden areas of the skull base. These pathways are described in step-by-step fashion with the aid of a wealth of color images and illustrations. The emphasis is on endoscopic anatomy, but in order to provide a holistic perspective, informative three-dimensional reconstructions are presented alongside the endoscopic images and radiologic images are included when appropriate. In effect, windows are opened on the anatomy so that the reader is guided on a journey throughout the skull base region. This anatomically oriented atlas will serve as an ideal learning tool for novice surgeons and will also prove an invaluable reference for the more experienced surgeon

This book identifies the 50 key scientific articles in the field of vascular and endovascular surgery. It provides a commentary to each carefully selected paper and explains why these papers are so important, thus providing every surgeon with the foundation stones of knowledge in this fast-moving area. There has been an exponential increase in the volume and quality of published research relating to vascular and endovascular surgery in recent decades. Among thousands of articles, a small fraction is truly "game changing." Such studies form the foundations of vascular surgery today and the selection of papers within this book provide the 50 landmark papers every 21st-century vascular and endovascular surgeon needs to know. A valuable reference not only to the established surgeon, but also to vascular surgery residents and trainees, as well as to more experienced surgeons as they continue to learn new techniques and approaches and to improve their knowledge of vascular disorders and treatments. The papers provide an evidence-based resource for those surgeons preparing for professional exams and may inspire clinicians to produce new research. About the Editors Juan Carlos Jimenez MD, MBA Professor of Surgery Gonda (Goldschmied) Vascular Center David Geffen School of Medicine at UCLA Los Angeles, California Samuel Eric Wilson, MD Distinguished Professor of Surgery and Chair Emeritus University of California Irvine Irvine, California

Patients with peripheral vascular disease (PVD) are at increased risk of death when compared with age-matched healthy controls. They are also, whether symptomatic or not, six times more likely to die within ten years when compared to patients without the disease. This excess mortality exists even if coronary artery disease is not clinically present, and makes the treatment of PVD a highly important and pressing topic. In this fully up-to-date text, Dr. Mukherjee and his excellent team of twenty-one contributors present the reader with all of the currently available clinical information for treating PVD patients effectively.

As societies have aged and aortic diseases have become more prevalent, advances in diagnostic imaging and surgical techniques have brought significantly improved results for patients. In cardiovascular surgery, important questions remain to be addressed, however. "Strategy for Cardio-aortic and Aortic Surgery" was the theme of the 7th Keio University International Symposium for Life Sciences and Medicine. Meeting in Tokyo, researchers and specialists in cardiac surgery from around the world discussed crucial issues in their field. Papers from the symposium, collected in this volume, cover a broad range of topics, including recent advances in diagnostic imaging, brain protection during aortic surgery, spinal protection during thoracoabdominal aneurysm repair, treatment of type A acute aortic dissection, and stent-grafts and less-invasive aortic surgery. This unique book provides valuable information especially for aortic, cardiovascular, and thoracic surgeons.

A comprehensive review the state-of-the-art in atherosclerosis of the arteries of the legs and feet. The authors discuss in detail the primary symptom-claudication-an intermittent pain in the leg or foot while walking, its predisposing factors, the current diagnostic methodologies, the impressive advances in the therapeutic armamentarium, and the need to screen for co-existing coronary artery disease. Additional chapters describe cutting-edge noninvasive angiography and vascular flow studies, specific drug therapy for claudication, regression of atherosclerosis therapy, gene therapy, and drug eluting stents for peripheral arterial disease. The authors also examine the epidemiology of LEAD, the effects of smoking and effective smoking cessation programs, its pathogenesis and its association with lipid abnormalities and hypertension, aggressive risk factor modification, and the need to measure the ankle brachial index of every patient over 45.

For more than 40 years, Rich's Vascular Trauma has been surgeons' #1 reference for the diagnosis and treatment of vascular injury in both civilian and military settings across the globe. The fully updated 4th Edition reflects recent changes in vascular injury patterns, wounds, and trauma care, drawing from current research and a wide variety of peer-reviewed publications to keep you up to date with the latest evidence-based management strategies and techniques. Written and edited by vascular surgeons who are also trauma specialists-civilian and military experts who have proficiency in both open-surgical and endovascular techniques-this must-have reference offers a global perspective on every aspect of the broad spectrum of vascular trauma. Covers all vascular surgery procedures required to stop hemorrhage and restore perfusion in vessels in the limbs, junctional areas, torso and neck, including damage control techniques such as shunting, and endovascular techniques such as REBOA and stenting. Addresses pre-hospital, emergency department, surgical, and endovascular stages of treatment in developed, austere and deployed settings, including a rich section on vascular trauma in multiple international settings that provides important context for the global surgical community. Includes nine new chapters covering prehospital management, endovascular suites, stent-grafts, selective aortic arch perfusion, extracorporeal systems and gathering evidence in vascular trauma, and more. Presents surgical techniques in step-by-step, highly illustrated detail, as well as high level, strategic decision-making such as the logistics of setting up an endovascular trauma service. Includes a new, rapidly digestible "Tips and Tricks" section summarizing how to execute essential vascular maneuvers and management steps to ensure that patients get the best outcomes. Emphasizes the current management of civilian vascular injuries while drawing upon the best available evidence, experience, and lessons learned from Afghanistan, Iraq, and the "urban battlefield." Contains an innovative chapter on the systems approach and quality improvement in vascular trauma, offering information and tactics for all providers wishing to understand how clinical systems underpin patient outcome and recovery. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.