Microcirculation is a rather new field which has been of predominant interest to basic scientists, linking togeth~r technical, hemodynamic, and biochemical aspects. The fmdings elaborated, however, are not only of theoretical interest, but bear in addition great clinical implications. In clinical cardiology this became quite evident by the use of tracers in order to study myocardial perfuSion and by the deSCription of certain clinical entities - such as angina with normal coro nary arteries - which are best explained by "disturbed microcirculation". With respect to this new developing theoretical and clinical field of cardiac microcirculation it was the aim of the Microcirculation Working Group of the European Society of Cardiology to have a symposium on which all different but clinically relevant aspects of cardiac microcirculation will be covered. This symposium, held in Heidelberg in January 1980, was planned not only for the exchange of concepts and ideas, but was expected to be in addition partially a teaching session; the basic scientists should be directed toward a better under standing of the clinical problems, and the clinicians should learn more about the basic mechanisms regulating substrate and ion exchange in such an impor tant organ as the heart, and furthermore the theoretical limitations of some of the diagnostic and therapeutical procedures should be taught. Without a lot of help we would never have succeeded in organizing the sym posium and editing its results.

The International Congresses of Angiology have had a 25-year tradition. Let us remember the 10 previous International Congresses, the first of which took place in Paris in 1952. On this occasion a stimulus for the foundation of the International Union, "Union Internationale d Angeiologie" came into existence. The period of 25 years is lon.qenough to evaluate the scientific progress which has been made in diagnosis, therapy and prevention of vascular diseases. Proceedings of the previous International Congresses of Angiology became attractive resources for scientific information in libraries all over the world. They represent really historic documents of remarkable development of angiology and wittness successful international cooperation in the settlement of serious medical problems of the twentieth century. The Proceedings of the XI. International Congress of Angiology held in Prague 1978 under the stimulating title "Adaptability of Vascular Wall" contains 284 original papers dealing with scientific and clinical research in arterial, venous and lymphatic circulation. The papers are incorporated into 12 chapters according to the main topics. In the first sections the questions of atherogenesis and thrombogenesis are discussed with regard to the adaptability of vascular wall in various metabolic, immunobiologic, and hemodynamic disorders. In the further sections attention is paid to new procedures in investigation, treatment, and prevention of arterial, venous, and lymphatic diseases. Peri pheral microangiopathies, renovascular hypertension, and coronary circulation represent another part."

Fundamentals of Frontline Surgery is an easy to read text, written by world class faculty, that provides clinicians with succinct and didactic information about what to do in high intensity, resource limited situations.With global conflicts and humanitarian emergencies on the rise, there has been a dramatic uptake in the number of volunteers for both military and humanitarian operations. This manual aids best practice and fast decision making in the field.

The first cardiovascular operation in Duesseldorf, a ligation of an open ductus arteriosus (Botallo), was performed in 1938 by E. K. Frey. During the Second World War and the subsequent years many difficulties hindered cardiovascular surgery in Duesseldorf. However, it was resumed on 3 May 1949 by Prof. Ernst Derra, again by ligating an open ductus arteriosus. This was the starting pOint of the successful cooperation between the cardiological and surgical working groups - the "birthday" of the Duesseldorf Heart Centre. Further highlights in cardiac surgery were the introduction of open heart surgery by means of surface-cool- ing hypothermia (9 February 1955) and extracorporeal circulation (21 February 1959) . In addition to cardiac catheterization and surgery in patients with acquired and congenital heart disease, the diagnosis and treatment of arrhythmias was one of the focal points of the centre. On 3 October 1961 the first pacemaker was implanted in a patient with a third-degree AV-block after he had been treated using an external device for about 1 year. In recent years interest has increasingly turned to the tachy- arrhythmias. Close cooperation between the medical and surgical teams made possible the application of new pacing techniques for the treat- ment of tachycardia. In patients with intractable arrhythmias, surgical interventions were made to eliminate the "focus" of the arrhythmia. In the past 2 years intraoperative electrophysiologic studies (endo-cardi- al and epicardial mapping) were applied to enhance the success of the surgical procedures.

Das Buch hebt auch in der 2. komplett uberarbeiteten und aktualisierten Auflage den interdisziplinaren Charakter der Behandlung des diabetischen Fusssyndroms hervor. Nur in einem ausgewogenen Zusammenspiel von operativ und nicht-operativ tatigen AErzten sowie den entsprechenden medizinischen Assistenzberufen ist eine umfassende und die Extremitat erhaltende Therapie moeglich. Die Umsetzung des Gelesenen in die Praxis erleichtern die therapeutischen Algorithmen und die vielen Handlungsempfehlungen, die die Autoren geben. Zahlreiche Abbildungen/Bildserien veranschaulichen daruber hinaus die Inhalte.

The Royal College of Surgeons' of England two-day "definitive surgical trauma skills course" is run by the authors. The course began in 1997 but a new syllabus has recently been put in place.The focus is on thoracic ,abdominal and vascular injuries, caused by both penetrating trauma, such as a knife, and ballistic trauma caused by guns.This Manual accompanies the course and it's aim is to "demystify the body" and show how to control massive blood loss. Interventions, whether they be military or civilian, are descrbed in full, and techniques derived from the battlefield and world-wide hotspots in trauma -are exemplified within this book.

The goal of Endovascular Skills: Guidewire and Catheter Skills for Endovascular Surgery has always been to provide a "step-by-step" approach to techniques and procedures that comprise one of the most exciting and rapidly developing specialties in medicine today: minimally invasive management of vascular disease. Endovascular technique has gone from being a novelty to a mainstay of vascular care and this edition of Endovascular Skills has been revised and expanded to reflect these changes. This book serves as a "how-to" guide for endovascular intervention and aims to assist clinicians in the development and refinement of skills that are now essential to vascular practice. The book introduces readers to strategy, vascular access, guidewire-catheter handling, and arteriography in a multitude of vascular beds. The knowledge base builds as the text progresses in much the same manner that the skill of the professional builds as experience is gained by performing more complex cases and managing complicated patterns of disease. The chapters progress to all aspects of endovascular therapy, including sheath access, balloon angioplasty, stents, and other treatment modalities.

From its initial clinical use, over 28 years ago, to its current extensive use (over 100,000 times annually in the US alone), balloon pump equipment has developed into sophisticated, computer--assisted technology for mechanically aiding circulation. This book fully and clearly explains the function and clinical application of IABP in various clinical conditions. In addition, it reviews all the new achievements and complications of balloon pumping, such as percutaneous sheathless balloon catheter insertion and the addition of various control and alarm systems to the drive console to assure patient safety. Because the effective clinical application of IABP involves more than familiarity with the device and implications for its use, Dr Bolooki also discusses the causes of cardiac failure and its pathophysiology; the reversibility of ventricular dysfunction; and the other assist devices frequently used in conjunction with IABP in cases of severe cardiac failure. Recent IABP studies that evaluated the effect of this device on short-- and long--term patient survival -- and on the extent of myocardial salvage after ischemia or infarction -- are also included in this extensively updated and expanded third edition.

Now in full color, Handbook of Patient Care in Vascular Diseases is a concise quick-reference guide to effectively diagnosing and treating patients with common arterial and venous vascular diseases. Chapter by chapter, content is presented in a convenient online format, and covers everything from the latest diagnostic methodologies to current catheter-based basics to post-op patient management. Diseases and conditions include diabetes mellitus, atherosclerosis, obesity, and more. Emphasizes patient management and care rather than the technicalities of surgical interventions. Thoroughly updated, incorporating recent advancements in endovascular technologies and procedures. Disease-specific chapters cover pathophysiology, pre-op management, diagnosis, examination, procedural planning, and follow-up. Practical, no-nonsense writing style designed for easy and quick absorption of material. Includes management checklists, referenced to current literature, that facilitate efficient care planning and activities. Enhance Your eBook Reading Experience: Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.

Vascular surgery and endovascular surgery are both modalities to treat vascular disease. Endovascular describes a minimally invasive approach commonly done through needle puncture and a sheath. Traditional vascular surgery is more invasive and involves incisions, which is more surgical in nature. This book provides vascular surgeons and trainees with the latest advances and techniques in vascular and endovascular surgery. Divided into seventeen sections the book covers procedures for numerous vascular disorders including lower limb ischemia, vascular graft infection, cancer-associated thrombosis, vascular leg ulcers, varicose veins and many more. Separate chapters discuss anaesthesia and ethical choices in vascular surgery. The comprehensive text is further enhanced by more than 200 clinical photographs, diagrams and tables to assist learning. Key points Comprehensive guide to latest advances and techniques in vascular and endovascular surgery Covers procedures for numerous different vascular disorders Includes discussion on anaesthesia and ethical choices in vascular surgery Features more than 200 images, diagrams and tables

With authoritative coverage of everything from recent discoveries in the field of vascular biology to recent clinical trials and evidence-based treatment strategies, Vascular Medicine, 3rd Edition, is your go-to resource for improving your patients' cardiovascular health. Part of the Braunwald family of renowned cardiology references, this updated volume integrates a contemporary understanding of vascular biology with a thorough review of clinical vascular diseases, making it an ideal reference for vascular medicine specialists, general cardiologists, interventional cardiologists, vascular surgeons, and interventional radiologists. Incorporates technologic advances in vascular imaging - including ultrasound, MRI, CTA, and catheter-based angiography - along with more than 230 new figures, providing an up-to-date and complete view of the vascular system and vascular diseases. Covers novel antithrombotic therapies for peripheral artery disease and venous thromboemboism, advances in endovascular interventions for aortic aneurysms, and today's best surgical treatments for vascular diseases. Includes seven new chapters: Pathobiology of Aortic Aneurysms; Pathobiology and Assessment of Cardiovascular Fibrosis; Large Vessel Vasculitis; Medium and Small Vessel Vasculitis; Epidemiology and Prognosis of Venous Thromboembolic Disease; Fibromuscular Dysplasia; and Dermatologic Manifestations of Vascular Disease. Discusses methods for aggressive patient management and disease prevention to ensure minimal risk of further cardiovascular problems. Keeps you current with ACC/AHA and ECC guidelines and the best ways to implement them in clinical practice. Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices

Providing a practical, current, evidence-based approach to all aspects of perioperative care for the patient with vascular disease, Vascular Anaesthesia is an essential read for all vascular anaesthetists, anaesthetic nurses and anyone else involved in the care of vascular patients throughout the world. Vascular Anaesthesia summarizes current knowledge, particularly on interventional procedures (radiological, diagnostic, and surgical). This book also equips the trainee anaesthetist with the scientific and clinical knowledge to pass the Final FRCA examination. It enables doctors to approach vascular surgical patients with a firm understanding of a particular procedure, particularly its risks and options for perioperative management based on current best practice. The management of the patient with vascular disease is evolving rapidly: this indispensible poket reference is of sufficient detail to update the regular and occasional vascular anaesthetist with current best practice for particular, common clinical scenarios. The book also equips the non-anaesthetic medical, nursing, and theatre staff with knowledge and understanding of all other aspects of perioperative care.

Cardiovascular Biomaterials presents current research mate- rial developed by contributors from universities und profes- sional laboratories in the UK, USA, Canada, and Germany, each recognised for their abilities in this field.The book begins with an introduction to the work of developing a new artificial artery, and proceeds through the topics of the problems and developments in heart valve replacements, car- diac assist devices, mechanical properties of arteries and arterial grafts, biostability of vascular prostheses, blood compatibility in cardiopulmonary bypass, collagenin cardio- vascular tissues and the pacemaker system. Researchers, practitioners, graduate students, and libraries will find the book of interest.

This volume explores the latest techniques used to study the field of tissue engineered vascular grafts (TEVGs). The chapters in this book cover a wide array of topics such as deriving vascular cells from monocytes and induced pluripotent stem cells; engineering vascular grafts using various biomaterials and stem cells, stem cell-derived, or primary vascular cells; biomaterial modification by anticoagulation molecules; vascular bioengineering technologies such as 3D bioprinting; and fabrication of TEVGs with different geometry and multiphase structures. This book also features protocols for grafting and evaluation of vascular grafts in animal models, vascular imaging in animals, and the quantification of blood vessel permeability. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Vascular Tissue Engineering: Methods and Protocols is a valuable resource for biomedical engineers, cell biologists, vascular surgeons, doctors, and nurses.

This book presents a practical overview of the widely used endovascular treatment of arterial emergencies, covering the majority of cases encountered in praxis. Including a wealth of high-quality images of arterial emergencies and treatment descriptions, it provides readers with essential information and shares insights into endovascular options. However, the book focuses on presenting common arterial emergencies from diagnosis to treatment only, without exhaustively describing all endovascular options. The clinical cases explore thoracic arterial emergencies, followed by abdominal emergencies and peripheral arterial emergencies. Rare clinical cases are also examined. The book offers interventional radiologists, vascular surgeons and cardiologists, as well as residents in these disciplines, a valuable tool for use in their everyday clinical praxis.

Vascular diseases are the leading cause of death worldwide. Distinguished clinical and surgical approaches have attempted to overcome its morbidity and mortality; still 17.9 million people die every year due to vascular affections. Stem cell therapy has emerged as a promising therapeutic strategy. Stem cells synthesize and secrete cytokines that promote cell recruitment, immunomodulation, extracellular matrix remodeling, angiogenesis, and neuroregeneration, all of which promote regeneration. Besides that, stem cells are also capable of differentiating in various cell types, being employed in tissue engineering. Preclinical and clinical investigations have reported efficacy of stem cell therapy for various vascular diseases. Even though results are encouraging, the studies demonstrate variation in stem cell type and origin, route and protocol for administration, and concomitant use of other treatment strategies, impairing easy interpretation of results and clinical application. The purpose of this book is to compile and comprise the current state of the evidence regarding stem cell therapy for each vascular disease, elucidating possible clinical applications. More than an objective guide for readers on the use of this novel treatment strategy, this publication will advocate for stem cell therapy use and development and will be of significant interest to physicians in a wide range of disciplines as well as researchers.

Following the popular and accessible at a Glance format, Vascular and Endovascular Surgery at a Glance demystifies the important concepts of vascular disease and vascular surgery. Featuring in- depth details of common vascular topics, to rarer presentations, this is an ideal guide for those interested in a variety of subjects relating to this rapidly expanding area. This is a must- read for any specialist at all levels who has an on-going commitment to vascular disease management and medical education. Vascular and Endovascular Surgery at a Glance: Comprehensively covers the key concepts and core practical procedures with superb illustrations Is a brilliant companion to the emerging curriculum for specialist vascular training Is an excellent source of information and management guidelines for interdisciplinary specialties Includes a companion website at www.ataglanceseries.com/vascular featuring a wide range of interactive multiple choice questions This title forms a succinct overview of vascular disease management, giving salient points relevant to general surgery examinations, for those requiring an in-depth yet manageable introduction to vascular diseases, and for those entering this prevalent field as a stand-alone specialty.

In this concise but authoritative book, the authors take the reader through the epidemiology, risk factors and the basic mechanism of coronary artery disease. In addition, they explain how coronary microvascular dysfunction can lead to angina, even after successful angioplasty following a heart attack. The methods for diagnosis and the options for treatment are explained, ending with a discussion of the evolution of coronary angioplasty from balloon catheters to novel, fully resorbable polymeric drug eluting stents. Enclosed is a list of currently available commercial devices, as well as a listing of experimental products under research and development, so that readers can appreciate the serious nature of this disease and have an understanding of how the medical device sector is attempting to address this major healthcare problem. Globally in 2010, ischemic heart disease was the cause of 13.3% of all deaths. In the US alone, the direct medical costs from coronary artery disease and stroke are currently estimated to be $126 billion per year, and are expected to rise to $309 billion by 2035.

This book, from the faculty and residents of one of the world's most respected hospitals, provides a comprehensive and concise approach to vascular disease. Beginning with the foundations of vascular disease and diagnosis, this text moves on to cover critical disease processes. Each section of the book, dedicated to a unique pathology, explains salient pathophysiology, presentation, diagnosis, treatment options, and outcomes. A special emphasis is given to both open and endovascular techniques and their related pitfalls. Additionally, reflecting the growing importance of evidence-based medicine, readers are provided with references to critical publications that underpin diagnostic and therapeutic recommendations. Diagnosis, treatment, and more are provided succinctly, allowing this text to be broad in focus while remaining in a convenient portable format. As a brief review for practicing physicians or a primary educational text for fellows, residents, and medical students, Cleveland Clinic Manual of Vascular Surgery is a valuable addition to everyone's library.

This book presents a comprehensive and state-of the-art approach to vascular disease for the geriatric patient, focusing on vascular pathology and interventions but also on perioperative care, anesthetic care, functional outcomes and quality of life, as well as ethical considerations that impact decision making. The book addresses open and endovascular interventions in different vascular beds, as well as preoperative workup and optimization, anesthetic considerations, all aspects and expectations of the postoperative care and recovery and is the only book to include specialize in the intricacies of the care of the geriatric patients, the challenging recovery and neurocognitive changes, and ethical considerations for the end stage geriatric patient or in the setting of postoperative complications. Written by experts in the field, each section addresses patient selection, pre-operative considerations, technical conduct of the most common operations with open or endovascular options, and avoiding complications. A brief review of the existing literature addressing the particular topic follows in each section. With its concise yet comprehensive summary of the field, Vascular Disease in Older Adults is the ultimate resource for geriatricians, cardiologists, surgeons, anesthesiologists, and all physicians of who care for the aging patient with vascular disease.

Vascular surgery has experienced remarkable growth and diversification in the last decade, especially with its embracing the disruptive endovascular technological revolution. Vascular surgeons remain the only group of specialists capable of total treatment of patients with vascular disease, providing medical, minimally invasive, and surgical therapy. Although vascular surgeons practice in all areas of the world, practice patterns in different areas naturally have both similarities and differences that reflect both regional patterns of disease, genetic characteristics of local peoples, cultural preferences for treatment, local political and economic situations, different access to resources and devices, as well as different training paradigms. Thus, the practice of vascular surgery has diversified and evolved in parallel in many areas, converging and diverging in many ways. Vascular Surgery: A Global Perspective provides the first review and comparison of the diversity of vascular surgery practice around the world. The book is grouped according to common vascular diseases such as aneurysmal and occlusive arterial disease, as well as venous and lymphatic disease and dialysis access. Each major disease topic includes multiple chapters written by expert specialists from around the world, each discussing their local approach to the disease and its treatment. Similarly, the status of vascular surgery practice is addressed, including discussion of the influence of payment systems on practice, patient access to the internet for information, training paradigms, and the legal system including malpractice. This textbook provides the first worldwide summary of the care of patients with vascular disease and will be of interest to a wide audience including vascular surgeons, vascular medical specialists, cardiologists, radiologists, internists, and family practice physicians.

This text provides a comprehensive, state-of-the-art review of catheter based approaches to valve and aortic diseases. The scope encompasses involve all the current and upcoming transcatheter aortic valve technologies as well as mitral, pulmonary and tricuspid valve technologies. Aortic diseases including transcatheter repair of descending aneurysms are included and the upcoming technologies designed to repair aortic dissections, traumatic injury, and ascending arch stent repair are highlighted. Catheter Based Valve and Aortic Surgery will be a useful tool for cardiac and vascular surgeons, interventional cardiologists, general cardiologists, and clinicians and researchers with an interest in these exciting new developments in structural heart and vascular diseases.

Administering the National Health Service (NHS) is asking to navigate without reliable and sufficient information. It is amazing how a national service costing more than GBP15,OOOM (1984) and employing more than 1 million has existed since 1948. It is likely that with better appropriate data there could be economies and great efficiency and effectiveness. Paradoxically there is much data on the NHS, published and unpublished, that has remained unexploited and unused. In this book we have taken up the challenges of showing the availability of data and its presentation so that clinicians, adminis trators, committee members and politicians can better understand the state and needs of the NHS. Why this book? Because it is not possible to make decisions without facts. There is too much data around that is unrelated to the needs of clinicians, administrators, committee members and politicians. It can be brought together to provide bases for de cisions and, more important, to show the gaps that exist and the need for more information. What does it contain? It includes social and demographic data, NHS facts and figures, manpower data on the use of the NHS and some examples of how quality can be assessed and promoted.

This text evolved as a response to numerous requests to present a simplified approach to the diagnosis and management of most of the common aspects of both cosmetic and medical venous disorders. The authors, representing experienced plebologists from several different primary disciplines, have attempted to present simplistic paradigm-oriented approaches on how to thoughtfully evaluate and manage common vein issues with contemporary solutions. Several areas of phlebology were not addressed in this text. The management of vascular malformations are beyond the scope of this text and were not covered in detail. Although indications for the appropriate use of IVC filters are discussed, the details about the specific devices, their placement and removal are also beyond the scope of this text. Deep venous obstruction from prior thrombosis, venous compression by arteries such as the compression of the left common iliac vein by the right common iliac artery and pelvic venous insufficiency can now be managed with minimally invasive image guided treatments; the technical aspects of such treatments are complex and not discussed in detail in this handbook. This book will increase the therapeutic skill of the practicing phlebologist and thus increase the quality of care for patients faced with problems related to venous disorders.

Over the past three decades, carotid artery stenting has evolved to become a promising and viable alternative to carotid endarterectomy, especially for patients deemed to have high surgical risks. In Carotid Artery Stenting: The Basics, Jacqueline Saw and a panel of international experts on carotid artery stenting discuss in depth the details of all contemporary aspects of carotid stenting, while reviewing supporting studies, guidelines, technical perspectives, and peri-procedural management. This textbook serves as a learning resource on the multifaceted management of patients with carotid artery stenosis, with the key focus on extracranial carotid artery stenting. Additional sections detail the specifics of setting up and maintaining a laboratory and discuss the preparation of the carotid artery stenting procedure from both the patient and operator's perspective. Authoritative and highly practical, Carotid Artery Stenting: The Basics is an accessible guide and valuable resource for today's cardiologists, radiologists, and vascular surgeons.