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Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Stem Cell Therapy for Vascular Diseases - State of the Evidence and Clinical Applications (Paperback, 1st ed. 2021)
Loot Price: R2,013
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Stem Cell Therapy for Vascular Diseases - State of the Evidence and Clinical Applications (Paperback, 1st ed. 2021)
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Vascular diseases are the leading cause of death worldwide.
Distinguished clinical and surgical approaches have attempted to
overcome its morbidity and mortality; still 17.9 million people die
every year due to vascular affections. Stem cell therapy has
emerged as a promising therapeutic strategy. Stem cells synthesize
and secrete cytokines that promote cell recruitment,
immunomodulation, extracellular matrix remodeling, angiogenesis,
and neuroregeneration, all of which promote regeneration. Besides
that, stem cells are also capable of differentiating in various
cell types, being employed in tissue engineering. Preclinical and
clinical investigations have reported efficacy of stem cell therapy
for various vascular diseases. Even though results are encouraging,
the studies demonstrate variation in stem cell type and origin,
route and protocol for administration, and concomitant use of other
treatment strategies, impairing easy interpretation of results and
clinical application. The purpose of this book is to compile and
comprise the current state of the evidence regarding stem cell
therapy for each vascular disease, elucidating possible clinical
applications. More than an objective guide for readers on the use
of this novel treatment strategy, this publication will advocate
for stem cell therapy use and development and will be of
significant interest to physicians in a wide range of disciplines
as well as researchers.
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