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New Frontiers in Lifestyle-Related Diseases (Hardcover, 2008 ed.)
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New Frontiers in Lifestyle-Related Diseases (Hardcover, 2008 ed.)
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It is my great pleasure to publish New Frontiers in
Lifestyle-Related Dis eases, the proceedings of the Showa
University International Symposium for Life Sciences, 3rd Annual
Meeting, held at Showa University on Sep tember 13, 2006. This
symposium was supported, in part, by Grants for the Promotion of
the Advancement of Education and Research in Graduate Schools and
Ordinary Expenses for Private Schools from the Ministry of
Education, Culture, Sports, Science, and Technology of Japan. On
behalf of Showa University, I would like to express my deepest
thanks to all the authors and editors for their great contribution
to the publication of this memorable book that accelerates research
activity in lifestyle-related diseases. Akiyoshi Hosoyamada, M.D.,
Ph.D. President, Showa University Tokyo, Japan September 2007 v
Preface The leading cause of death in Western countries and some
developing countries is atherosclerotic cardiovascular diseases.
Among them, acute myocardial infarction is the most common type of
fatal disease, caused by the progression of atherosclerosis
characterized by accumulation of choles terol in vascular walls.
Development of atherosclerosis is greatly enhanced by major risk
factors for cardiovascular diseases such as obesity, hyperlip
idemia, diabetes (hyperglycemia), and hypertension. Among those,
obesity frequently initiates a metabolic change that subsequently
induces hyperlip idemia, diabetes, hypertension, and eventually
atherosclerotic cardiovascu lar diseases. Because obesity and its
related disorders largely depend on lifestyle factors such as high
calorie intake and low physical activity, a series of disorders are
termed lifestyle-related diseases.
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