This book is the introduction to a series of e-books dedicated to
the physiology and pathophysiology of neuroglia. The topic of
neuroglia is generally overlooked in neuroscience curricula across
the world, the main attention being focused on the description of
excitability of neurons and neuronal networks. The neuroglia, being
electrically non-excitable, are universally regarded as supportive
cells which do not contribute to information processing. This
oversimplified view, however, ignores the tremendous importance of
brain homeostasis, which is imperative for the ongoing activity of
neuronal networks. It also ignores the truth that specialization of
neurons and their ability for rapid propagation and multi-level
integration of signals become possible only because of delegation
of homeostatic abilities to neuroglia. Furthermore, glial cells
contribute to information processing as they can modulate neuronal
synaptic transmission. Finally, neuroglia provide the only system
of brain defense and as such these cells are intimately involved in
all types of neuropathologies, and contribute to both
neuroprotection and regeneration of the nervous system. The e-books
in this series provide a platform for in-depth learning of all
aspects of neuroglial cells function in health and disease.
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