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Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill (Hardcover, 1st ed. 2018)
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Antibiotic Pharmacokinetic/Pharmacodynamic Considerations in the Critically Ill (Hardcover, 1st ed. 2018)
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This book provides unique insights into the issues that drive
modified dosing regimens for antibiotics in the critically ill.
Leading international authors provide their commentary alongside a
summary of existing evidence on how to effectively dose
antibiotics. Severe infection frequently necessitates admission to
the intensive care unit (ICU). Equally, nosocomial sepsis often
complicates the clinical course in ICU. Early, appropriate
application of antibiotic therapy remains a cornerstone of
effective management. However, this is challenging in the critical
care environment, given the significant changes in patient
physiology and organ function frequently encountered. Being
cognisant of these factors, prescribers need to consider modified
dosing regimens, not only to ensure adequate drug exposure, and
therefore the greatest chance of clinical cure, but also to avoid
encouraging drug resistance.
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