The process of discovery in science and technology may require
investigation of a large number of features, such as factors, genes
or molecules. In Screening, statistically designed experiments and
analyses of the resulting data sets are used to identify
efficiently the few features that determine key properties of the
system under study.
This book brings together accounts by leading international
experts that are essential reading for those working in fields such
as industrial quality improvement, engineering research and
development, genetic and medical screening, drug discovery, and
computer simulation of manufacturing systems or economic models.
Our aim is to promote cross-fertilization of ideas and methods
through detailed explanations, a variety of examples and extensive
references.
Topics cover both physical and computer simulated experiments.
They include screening methods for detecting factors that affect
the value of a response or its variability, and for choosing
between various different response models. Screening for disease in
blood samples, for genes linked to a disease and for new compounds
in the search for effective drugs are also described. Statistical
techniques include Bayesian and frequentist methods of data
analysis, algorithmic methods for both the design and analysis of
experiments, and the construction of fractional factorial designs
and orthogonal arrays.
The material is accessible to graduate and research
statisticians, and to engineers and chemists with a working
knowledge of statistical ideas and techniques. It will be of
interest to practitioners and researchers who wish to learn about
useful methodologies from within their own area as well as
methodologies that can be translated from one area to another.
General
Imprint: |
Springer-Verlag New York
|
Country of origin: |
United States |
Release date: |
October 2010 |
First published: |
2006 |
Editors: |
Angela Dean
• Susan Lewis
|
Dimensions: |
235 x 155 x 18mm (L x W x T) |
Format: |
Paperback
|
Pages: |
332 |
Edition: |
Softcover reprint of hardcover 1st ed. 2006 |
ISBN-13: |
978-1-4419-2098-0 |
Categories: |
Books >
Science & Mathematics >
Mathematics >
Probability & statistics
|
LSN: |
1-4419-2098-6 |
Barcode: |
9781441920980 |
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