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Introduction to Genomic Signal Processing with Control (Hardcover)
Loot Price: R4,442
Discovery Miles 44 420
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Introduction to Genomic Signal Processing with Control (Hardcover)
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Studying large sets of genes and their collective function requires
tools that can easily handle huge amounts of information. Recent
research indicates that engineering approaches for prediction,
signal processing, and control are well suited for studying
multivariate interactions. A tutorial guide to the current
engineering research in genomics, Introduction to Genomic Signal
Processing with Control provides a state-of-the-art account of the
use of control theory to obtain intervention strategies for gene
regulatory networks. The book builds up the necessary molecular
biology background with a basic review of organic chemistry and an
introduction of DNA, RNA, and proteins, followed by a description
of the processes of transcription and translation and the genetic
code that is used to carry out the latter. It discusses control of
gene expression, introduces genetic engineering tools such as
microarrays and PCR, and covers cell cycle control and tissue
renewal in multi-cellular organisms. The authors then delineate how
the engineering approaches of classification and clustering are
appropriate for carrying out gene-based disease classification.
This leads naturally to expression prediction, which in turn leads
to genetic regulatory networks. The book concludes with a
discussion of control approaches that can be used to alter the
behavior of such networks in the hope that this alteration will
move the network from a diseased state to a disease-free state.
Written by recognized leaders in this emerging field, the book
provides the exact amount of molecular biology required to
understand the engineering applications. It is a self-contained
resource that spans the diverse disciplines ofmolecular biology and
electrical engineering.
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