1,3-Pyrimidine Derivatives (Paperback)

There has been growing menace of antibiotic resistance in recent past owing to a number of reasons such as self medication and non-compliance on parts of patients with regard to complete dosage regimen. Medicinal chemists are hard pressed to bring about new molecules to cater to this need. 1,3-pyrimidine derivatives have been explored by a number of scientists worldwide and such these derivatives have emerged potential lead molecules for development of newer antimicrobial moieties. The present work reports the syntheses and evaluation of some 2-(6'-fluorobenzothiazol-2'-ylamino)-4,6-(disubstituted thiouriedo) -1,3-pyrimidine derivatives. Some of the synthesized derivatives showed excellent activity against Gram +ve bacteria Staphyllococcus aureus, Bacillus subtilis, and Gram -ve bacteria Escherichia coli and Pseudomonas aeruginosa. The contents of this book must make an excellent read for those interested in antibiotic research and allied interests.

General

Imprint:	Lap Lambert Academic Publishing
Country of origin:	Germany
Release date:	April 2012
First published:	April 2012
Authors:	Anoop Kumar Pathak • Viney Chawla • Shailendra K. Saraf
Dimensions:	229 x 152 x 7mm (L x W x T)
Format:	Paperback - Trade
Pages:	116
ISBN-13:	978-3-8484-8835-3
Categories:	Books > Science & Mathematics > Chemistry > Organic chemistry > General
LSN:	3-8484-8835-3
Barcode:	9783848488353

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