An important factor that affects the duration, complexity and cost
of a clinical trial is the endpoint used to study the treatment's
efficacy. When a true endpoint is difficult to use because of such
factors as long follow-up times or prohibitive cost, it is
sometimes possible to use a surrogate endpoint that can be measured
in a more convenient or cost-effective way. This book focuses on
the use of surrogate endpoint evaluation methods in practice, using
SAS and R.
General
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