In this issue, the Guest Editors have focused on recent advances in
liver disease related to disturbances in hemostasis and
coagulation. The work emphasizes the multifaceted aspects of
coagulation disorders in liver disease from hypo-coagulable to
hyper-coagulable states and the limitations of conventional tests
such as the INR to shed light on relative bleeding risk or on
underlying pathophysiology in a given patient. Articles are written
by leaders in the field from multiple disciplines and from around
the world. In each article, the state of the art is discussed along
with its limitations. The issue sheds light on recent advances,
explores areas of controversy, and thus, addresses the need of
combined clinical and laboratory investigation.
General
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