Controlled Release of Drugs from Liposomes Using Ultrasound (Paperback)

Liposomes, vesicles with one or more lipid bilayers entrapping an inner aqueous core, are widely used as drug delivery systems. When liposomes are smaller than 100 nanometers (nano liposomes) they have a unique capability of selectively accumulating in tumors and inflamed tissues. This phenomenon, known as the enhanced permeability and retention (EPR) effect, is related to the relatively high 'leakiness' of blood vessels in these diseased tissues. In this book, we present a novel approach for triggering drug release from liposomes at the target site, by use of a remote trigger - low frequency ultrasound. The book includes detailed descriptions of formulation, characterization, and in vivo performance of liposome-based drugs, with focus and insights into the biophysical phenomena governing ultrasound-induced liposomal drug release. Special attention is given to the principles needed to formulate ultrasound-responsive liposomes. The book is intended for people entering the field of liposome-based drug delivery as well as experienced scientists seeking fundamental understanding of the mechanism by which ultrasound interacts with lipid bilayers.

General

Imprint:	VDM Verlag
Country of origin:	Germany
Release date:	July 2010
First published:	July 2010
Authors:	Avi Schroeder • Joseph Kost • Yechezkel Barenholz
Dimensions:	229 x 152 x 7mm (L x W x T)
Format:	Paperback - Trade
Pages:	112
ISBN-13:	978-3-639-24728-2
Categories:	Books > Science & Mathematics > Biology, life sciences > Biochemistry > General
LSN:	3-639-24728-0
Barcode:	9783639247282

Is the information for this product incomplete, wrong or inappropriate? Let us know about it.

Does this product have an incorrect or missing image? Send us a new image.

Is this product missing categories? Add more categories.

Review This Product

No reviews yet - be the first to create one!