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Organization of Afferents from the Brain Stem Nuclei to the Cerebellar Cortex in the Cat (Paperback)
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Organization of Afferents from the Brain Stem Nuclei to the Cerebellar Cortex in the Cat (Paperback)
Series: Advances in Anatomy, Embryology and Cell Biology, 62
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The afferent connections of the cerebellar cortex of the cat have
been extensively in- vestigated by Alf Brodal and his collaborators
using retrograde degeneration methods. These experiments (reviewed
in Larsell and Jansen 1972) established that cerebellar corti- cal
afferents arise from widespread areas of the brain stem and spinal
cord. Brain stem nuclei shown to provide input to the cerebellar
cortex included the pontine nuclei, the medial and descending
vestibular nuclei, vestibular cell group x, the lateral reticular
nucleus, the perihypoglossal nuclei, the paramedian reticular
nucleus, the inferior olive, and the external cuneate nucleus. In
addition, the red nucleus and certain of the raphe nuclei were
thought to send fibers to the intracerebellar nuclei, but not to
the cortex. With the advent of the horseradish peroxidase (HRP)
technique, new information on the distribution and organization of
cerebellar cortical afferents has recently be- come available. Thus
Gould and Graybiel (1976) demonstrated that afferents to the cat
cerebellar cortex arise from a previously undescribed lateral
tegmental cell group at the level of the isthmus and from the
intracerebellar nuclei, as well as from the classic precerebellar
nuclei. Moreover, these studies showed that fibers from the
vestibular nuclei, previously thought to be distributed only to the
flocculonodular lobe and uvula, reach widespread areas of the
cerebellar cortex. Experiments by other investi- gators have
established that the cerebellar cortex of the cat receives
afferents from cer- tain of the raphe nuclei (Shinnar et al. 1975;
Taber Pierce et al.
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