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Books > Professional & Technical > Biochemical engineering > Biotechnology
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Models and Algorithms for Biomolecules and Molecular Networks (Hardcover)
Loot Price: R2,828
Discovery Miles 28 280
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Models and Algorithms for Biomolecules and Molecular Networks (Hardcover)
Expected to ship within 12 - 17 working days
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The subjects of the book are biomolecules and biomolecular
networks. The first part of the book will cover the areas of
structural and geometric models of biomolecules and their shape
characterization. First, there will be a discussion of geometry of
proteins, including voids and pockets, their scaling properties and
origin, and how to effectively use them to infer and characterize
the biological functions of proteins, as well as the detection of
backbone similarity of proteins regardless of the sequence
ordering. This will be followed by a discussion of the development
of sampling techniques for conformations of biomolecules, and
effective scoring functions to identify those that are similar to
native structures. Then, there will be a discussion on models and
computational techniques for studying folding and dynamics of
protein molecules. The second part of the book will cover
interaction networks of biomolecules. This will include stochastic
models for networks with small copy numbers of molecular species,
as those arising in genetic circuits, protein synthesis, and
transcription binding, and algorithms of computing the properties
of stochastic molecular networks. There will be a section on signal
transduction networks that arise, for example, complex interactions
between the numerous constituents such as DNA, RNA, proteins and
small molecules in a complex biochemical system such as a cell.
Experimental protocols and algorithmic methodologies necessary to
synthesize these networks will also be included. Of special
interest will be the problem of synthesizing these networks from
double-causal experimental evidences and methods for reverse
engineering such networks based on experimental protocols.
General
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