The ability to predict the behavior of fermentation systems
enhances the possibility of optimizing their performance.
Mathematical equations of model systems represent a tool for this
and the most recent advances in computer hardware and software have
made the approach more effective than previous simplistic attempts.
The current knowledge of biochemical microbial pathways and the
experience in optimization of chemical reactors combined with
extremely powerful and accessible computers, loaded with easy to
use software and mathematical routines, are changing the way
processes are being developed and operated.
This book has been written for all those who work with microbial
cultures, providing a useful, quick and contemporary re-education
for practitioners and students alike, breaking through
interdisciplinary barriers. Biologists, engineers and biochemists
will benefit from the methods of microbial process description and
optimization based on mathematical equations. The basic techniques
of modeling the bio-system are summarized in Part I. The useful
concept of mass balancing is introduced in Part II for those who
are not used to this simple and very useful engineering tool. An
extensive and descriptive case study of a selected fermentation
bio-process in Part III elucidates further the concepts of very
pragmatic mathematical modeling of bioreactor systems.
The volume outlines how to simply develop mathematical models of
microbial systems and demonstrates their power to: guide and
minimize the experimental work; check the consistency of
experimental results; predict the behavior of the bio-system and
analyze biocatalytic processes; diagnose the anomalies in the
microbial culture behavior and optimize the performance of
bioreactors.
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