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Books > Medicine > Pre-clinical medicine: basic sciences > Human reproduction, growth & development > Reproductive medicine > Infertility & fertilization
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Male & Female Infertility - Genetic Causes, Hormonal Treatments & Health Effects (Hardcover, New)
Loot Price: R4,642
Discovery Miles 46 420
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Male & Female Infertility - Genetic Causes, Hormonal Treatments & Health Effects (Hardcover, New)
Expected to ship within 12 - 17 working days
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Infertility is a major increasing concern. As the male factor
contributes to about half of the infertility cases, sperm analysis
is extremely important for diagnosis and investigation of
infertility. In this book, the cytometric techniques used to
evaluate sperm DNA/chromatin integrity together with some other
functional properties of the male gamete are described and
advantages and limitations are discussed. In addition, the authors
provide an overview of how antioxidative and redox systems
participate in spermatogenesis and in pathological conditions, such
as heat stress, in the testes. Oxidative stress-induced damage to
both oocytes in vivo and embryos in culture are also examined, as
well as the role of ROS signalling in embryo development.
Furthermore, endometriosis is an oestrogen-dependent disease which
affects 6% to 30% of women in reproductive age and is associated
with infertility in approximately 60% of cases. In this book,
classic and recently proposed etiopathogenic mechanisms or
endometriosis-related infertility are discussed, as well as some
aspects of its clinical investigation and medical treatment. Other
chapters in this book assess the capability of combining of
Anti-Mullerian hormone (AMH) and embryo quality as predictors of
pregnancy outcome and an examination of how the use of animal
models can help us to understand the female reproductive system and
the aetiology of some female infertile disorders.
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