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Books > Science & Mathematics > Biology, life sciences > Life sciences: general issues > Neurosciences
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Can a Virus Cause Schizophrenia? - Facts and Hypotheses (Paperback, Softcover reprint of the original 1st ed. 2003)
Loot Price: R4,309
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Can a Virus Cause Schizophrenia? - Facts and Hypotheses (Paperback, Softcover reprint of the original 1st ed. 2003)
Series: Neurobiological Foundation of Aberrant Behaviors, 6
Expected to ship within 10 - 15 working days
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The purpose ofthis book isto provide acritical appraisal
oftheconcept thatschizophreniacan becaused by viralinfections. The
ability of viruses to cause psychiatric symptoms is not in question
- the mental depression following a bout with mononucleosis or
hallucinations associated with herpesencephalitisarewell-described
examples. However, aviraloriginfor chronic disorders such as
autism, schizophrenia, and bipolar disorder, is another matter. The
claim of an infectious etiology for these disorders has
beenmetinthemainstream scientific community byavagueskepticism that
occasionally erupts into stringent criticism. Too often, however,
the viral hypotheses of these disorders is simply disregarded;
marginalized with the hopethat itwillgoaway sothatthe "serious"
researchaimed atuncovering therealcauseoftheseillnesses
willnotloseitsfocus.This beingsaid, much of the criticism is valid,
and as a researcher with formal training in both neuroscience and
viral immunology, I view the proposed viral etiology of
thesedisorderswithaskepticaleye. Nevertheless, one cannot ignore
the growing number of well-performed studies pointing to the role
of viral infections as important antecedents of schizophreniaand
other disorders inthe schizophreniaspectrum. Inthe last 30 years
there have been hundreds of articles in peer-reviewed journals
presenting
evidenceorpositingtheoriestosuggestthatatleastsomecasesof
schizophrenia have a viral origin. Moreover, many schizophrenia
experts have been calling for the recognition that schizophrenia
isa heterogeneous group of disorders that may have different
causes. This idea of disease heterogeneity is reaching a crescendo,
and there is undoubtedly a place for viruses among alternative
etiologies; but we have to look. The intellectual climate
tolooknowisbetterthanitwas20yearsago, inpartbecause inthe last 2
decades a number of chronic diseases of unknown etiology (e.g.
gastric ulcers, Kaposi's sarcoma, hepatocellular carcinoma) have
been ascribedtoinfectiouscauses.
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