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Mouse Models in the Study of Genetic Neurological Disorders (Hardcover, 1999 ed.)
Loot Price: R5,493
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Mouse Models in the Study of Genetic Neurological Disorders (Hardcover, 1999 ed.)
Series: Advances in Neurochemistry, 9
Expected to ship within 10 - 15 working days
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The number of mouse models that are available for the study of
human genetic neurological disorders is large and growing rapidly.
Therefore, it was difficult to select the models that were reviewed
in this volume. Clearly, there are important models that are not
discussed, and perhaps a volume twice this size would have been
more appropriate. Moreover, the pace at which new models are being
developed and analyzed is rapid. As this volume goes to press, I am
sure that additional mouse genes responsible for naturally
occurring neurological disorders are being discovered and that many
new transgenic and mutant mouse strains are being developed.
Therefore, this volume should not be viewed as a comprehensive
compendium, but rather as an update of work in progress. It is
exhilarating to witness the fast pace at which these models are
being established as important tools in the study of basic
neuroscience and neurological disorders. It will be even more
exciting to see their utilization in the development and testing of
therapeutic interventions for these diseases. I would like to thank
each of the authors who have contributed to this volume for their
time and their expertise. I would also like to thank Drs. Timothy
Coetzee and Joshua Corbin for their advice in the selection of the
topics covered. I am deeply indebted to Dr. Kunihiko Suzuki, who
first approached me with the idea for this volume, for his guidance
throughout its preparation.
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