Neuropsychiatry stands to benefit enormously from the new
research framework afforded by the sequencing of the human genome
and from examining the role of molecular genetics on the clinical
presentation of psychiatric patients. A solid foundation is
essential if novel genetic breakthroughs are to be translated to
successful clinical agents. However, this new research program is
magnitudes more complex than any enterprise embarked on hitherto
and requires the development, validation and deployment of novel
behavioural and neurophysiological phenotypes in order to unravel
the pathologies within neural functional systems. This Special
Issue provides an introduction to some important findings and
implications for neuropsychiatry. The role of specific functional
polymorphisms - including genomic mutations - as well as generalist
genes are explored in childhood, adolescence and adulthood in terms
of their modulatory roles on variables present at the level of
clinical diagnosis as well as those evident at the level of
intermediate neurocognitive and neurophysiological phenotypes, such
as emotional reactivity, working memory, executive function,
episodic memory and general intelligence. Methodological
considerations of this research enterprise are discussed, such as
genome wide association studies, the role of cognitive ontologies
for neuropsychiatric phenomics as well as possible novel cognitive
endophenotypes.
General
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!