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Nuclear G-Protein Coupled Receptors - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2015)
Loot Price: R3,911
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Nuclear G-Protein Coupled Receptors - Methods and Protocols (Paperback, Softcover reprint of the original 1st ed. 2015)
Series: Methods in Molecular Biology, 1234
Expected to ship within 10 - 15 working days
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Nuclear G-Protein Coupled Receptors: Methods and Protocols is a
compilation of a number of conceptual and methodological aspects
important for the validation and characterization of intacrine
signaling systems. To date, the best-characterized intracrine
signaling system is that of angiotensin II (Ang II), covered in
depth in various chapters. Methodology to study the subcellular
localization and function of GPCRs and other signaling systems is
provided, as well as numerous chapters focusing on methods designed
to understand signaling mediated by nuclear and other internal
GPCRs. Methods are also described to study the formation of second
messengers such as cAMP and to study the trafficking of receptors
from the cell surface. Written in the successful Methods in
Molecular Biology series format, chapters include introductions to
their respective topics, lists of the necessary materials and
reagents, step-by-step, readily reproducible protocols, and notes
on troubleshooting and avoiding known pitfalls. Authoritative and
easily accessible, Nuclear G-Protein Coupled Receptors: Methods and
Protocols seeks to serve both professionals and novices with
state-of-the-art approaches to characterize what is becoming a
common theme in cellular signaling.
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