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Pulmonary Hypertension Related to Aminorex Intake DNA Injuries, Their Repair, and Carcinogenesis Soft Tissue Tumors in the Rat Visceral Candidosis (Paperback, Softcover reprint of the original 1st ed. 1977)
Loot Price: R4,223
Discovery Miles 42 230
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Pulmonary Hypertension Related to Aminorex Intake DNA Injuries, Their Repair, and Carcinogenesis Soft Tissue Tumors in the Rat Visceral Candidosis (Paperback, Softcover reprint of the original 1st ed. 1977)
Series: Current Topics in Pathology, 64
Expected to ship within 10 - 15 working days
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In 1967 cardiologists in Switzerland were struck by the sudden
increase in the number of cases of so-called primary pulmonary
hypertensive disease (PPHD). Up untill966, the cardiology centers
in Switzerland had not seen more than one or two cases a year, but
this number suddenly multiplied by ten or twenty times. At the June
1968 meeting ofthe Swiss Society of Cardiology, Gurtner et al.
(1968b) presented a paper which raised the question whether the
vascular types of cor pulmonale had increased. They also raised the
question about the possible responsibility of environmental
factors, such as toxins or drugs, in causing this increase.
Krrihenbuhl et al. (1968) first suggested the possible
responsibility of anorexigenic drugs, but no proof was provided.
Soon after this, the cardiology team in Bem (Gurtner et al., 1968a)
published their report, which resumed and completed the
above-mentioned prelim inary communication; 31 cases of PPHD, among
which 17 had taken an anorexigenic drug, aminorex fumarate
(Menocil, Cilag), were reported. The importance of this work was
soon recognized and it was followed by several meetings (in Vienna,
Hannover, and Burgenstock) and two round tables sponsored by the
Swiss Society of Cardiology (in Montreux and Basel)."
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