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Books > Medicine > Clinical & internal medicine > Haematology
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Coagulation and Blood Transfusion - Proceedings of the Fifteenth Annual Symposium on Blood Transfusion, Groningen 1990, organized by the Red Cross Blood Bank Groningen-Drenthe (Paperback, Softcover reprint of the original 1st ed. 1991)
Loot Price: R3,018
Discovery Miles 30 180
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Coagulation and Blood Transfusion - Proceedings of the Fifteenth Annual Symposium on Blood Transfusion, Groningen 1990, organized by the Red Cross Blood Bank Groningen-Drenthe (Paperback, Softcover reprint of the original 1st ed. 1991)
Series: Developments in Hematology and Immunology, 26
Expected to ship within 10 - 15 working days
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While the enzyme cascade that allows coagulation is well known
physiologically, its elegant practical examples are vividly
demonstrable in the clinical application of blood and components
for the treatment of bleeding problems in surgery, trauma or in
congenital deficiency in patients. This volume provides the
fundamental and recent understanding relating to coagulation
pathways, recombinant technology and other methods for coagulation
factor production, up to date laboratory assay, preservation of
cellular and plasma components, and their clinical use in surgery
and medicine, including the immuno response to repeated challenge
to contaminating protein in coagulation factor concentrates. The
interrelated but multi-disciplinary chapters have been integrated
in four sections: Principles and Fundamentals: Mechanism of
thrombin formation; structure -- function relationship of
coagulation proteins, role of calcium and anticoagulant: blood
collection on haemostatic potential of plasma proteins and
platelets; Factor VIII yields from anticoagulant exchanged plasma.
Preservation Aspects: Platelet function preservation, platelet
interaction with vessel wall; trends in the use of coagulation
factor concentrate; immuno purification of Factor VIII; structural
and fundamental properties of recombinant coagulation factors.
Laboratory Aspects: Platelets counting and function testing;
platelet crossmatch predictive value; clinical efficacy of platelet
concentrate; protein C and protein S; principle of coagulation
factor assay; standardisation of clotting factor assays; clinical
efficacy of clotting factor concentrates. Clinical Consequences
General
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