Immunosuppressant Analogs in Neuroprotection (Paperback, Softcover reprint of the original 1st ed. 2003)

An authoritative survey of the most recent scientific evidence showing how cyclosporin, FK-506, and their analogs-the neuroimmunophilins-evolved from being purely immunosuppressant "drugs" to neuroprotective "agents". The book focuses on recent preclinical evidence that demonstrates the neurotrophic/neuroprotective effects of immunosuppressants when administered alone or when combined with neural transplantation therapy in animal models of neurological disorders. It also discusses their efficacy and mechanisms of action in vitro and in vivo models of CNS disease, and provides laboratory studies with compelling clinical indications for Alzheimer's disease, Huntington's disease, stroke, traumatic brain injury, spinal cord injury, ALS, sciatic nerve injury, and drug addiction.

General

Imprint:	HumanaPress
Country of origin:	United States
Release date:	December 2012
First published:	2003
Editors:	Cesario V. Borlongan • Ole Isacson • Paul R Sanberg
Dimensions:	229 x 152 x 22mm (L x W x T)
Format:	Paperback
Pages:	378
Edition:	Softcover reprint of the original 1st ed. 2003
ISBN-13:	978-1-4684-9742-7
Categories:	Books > Medicine > Clinical & internal medicine > Neurology & clinical neurophysiology
LSN:	1-4684-9742-1
Barcode:	9781468497427

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