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Cell Polarity Signaling - Methods and Protocols (Hardcover, 1st ed. 2022)
Loot Price: R6,460
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Cell Polarity Signaling - Methods and Protocols (Hardcover, 1st ed. 2022)
Series: Methods in Molecular Biology, 2438
Expected to ship within 10 - 15 working days
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This volume explores detailed methods to investigate various
aspects of biology related to cell polarity, or asymmetry within a
cell. Molecular, cellular, and tissue-level regulation and function
as well as diseases caused by impairment of cell polarity are
explored by these methods. Beginning with advanced imaging and
biochemical methods, the book continues with planar cell polarity
(PCP) signaling in morphogenesis in diverse developmental contexts,
apicobasal (AB) cell polarity in development and diseases, as well
as directional cell migration and biomechanics in cell polarity.
The collection includes the usage of a wide variety of model
systems and an extensive array of techniques, including genetic,
imaging, biochemical, and biomechanical. Written for the highly
successful Methods in Molecular Biology format, chapters include
introductions to their respective topics, lists of the necessary
materials and reagents, step-by-step, readily reproducible
laboratory protocols, and tips on troubleshooting and avoiding
known pitfalls. Authoritative and comprehensive, Cell Polarity
Signaling: Methods and Protocols aims to enable researchers to
delve into the stimulating field of cell polarity and contribute to
our understanding of how coordinated control of protein stability,
trafficking, membrane retention, post-translational modification,
and dynamic organization leads to active regulation of cell
polarity. Chapter 29 is available open access under a Creative
Commons Attribution 4.0 International License via
link.springer.com.
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