Lipid Oxidation in Health and Disease (Hardcover)

Oxidative modification of lipids and phospholipids-including radical damage, halogenation, and nitration-result in significant changes to the chemical properties of the molecules, which in turn have a major effect on their biochemical functions. Lipid oxidation has long been regarded as a deleterious process responsible for lipid rancidity, loss of function, and generation of toxic products. However in recent years, research has also focused on the non-detrimental physiological and pathological effects of these chemical reactions. Lipid Oxidation in Health and Disease provides an up-to-date review of the role of oxidized lipid products in physiological and pathophysiological processes. Covering the diverse topics that contribute to research in this important field, this book explores: The mechanisms of lipid oxidation, both enzymatic and non-enzymatic Antioxidant defenses and lipid oxidation Lipid oxidation products and cell signaling The roles of oxidized lipids in specific diseases-including cardiovascular, neurodegenerative, and metabolic disorders, as well as in cancer Drug targeting and the therapeutic potential of oxidized lipids Accurate measurement of the formation of lipid oxidation products and investigation of their biological effects and roles in disease are critical to biomedical science and new targeted therapeutics. Written by acknowledged experts in the field, this book provides a broad survey of both established knowledge and recent findings on the action of oxidized lipid products on cell signaling and gene expression in health and disease.

General

Imprint:	Apple Academic Press Inc.
Country of origin:	Canada
Series:	Oxidative Stress and Disease
Release date:	March 2015
First published:	2015
Editors:	Corinne M. Spickett • Henry Jay Forman
Dimensions:	229 x 152 x 30mm (L x W x T)
Format:	Hardcover
Pages:	440
ISBN-13:	978-1-4822-0285-4
Categories:	Books > Science & Mathematics > Biology, life sciences > Molecular biology Books > Medicine > Clinical & internal medicine > Endocrinology > General Books > Science & Mathematics > Biology, life sciences > Biochemistry > Lipids Books > Science & Mathematics > Biology, life sciences > Cellular biology > General Promotions
LSN:	1-4822-0285-9
Barcode:	9781482202854

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