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Books > Science & Mathematics > Biology, life sciences > Biochemistry > Lipids

Lipoxygenases in Inflammation (Hardcover, 1st ed. 2016): Dieter Steinhilber Lipoxygenases in Inflammation (Hardcover, 1st ed. 2016)
Dieter Steinhilber
R4,749 R3,688 Discovery Miles 36 880 Save R1,061 (22%) Ships in 12 - 17 working days

Oxidation of polyunsaturated fatty acids by lipoxygenases leads to a variety of fatty acid metabolites which play important roles in physiology but also in pathophysiology. Data accumulated during the last decade point to the fact that lipoxygenase metabolites are involved in host defence reactions, cardiovascular system and contribute to the development of inflammatory and allergic diseases, cardiovascular disease and cancer. This PIR volume summarizes the physiological and pathophysiological functions of lipoxygenases.

Lipoxygenases in Inflammation (Paperback, Softcover reprint of the original 1st ed. 2016): Dieter Steinhilber Lipoxygenases in Inflammation (Paperback, Softcover reprint of the original 1st ed. 2016)
Dieter Steinhilber
R3,715 Discovery Miles 37 150 Ships in 10 - 15 working days

Oxidation of polyunsaturated fatty acids by lipoxygenases leads to a variety of fatty acid metabolites which play important roles in physiology but also in pathophysiology. Data accumulated during the last decade point to the fact that lipoxygenase metabolites are involved in host defence reactions, cardiovascular system and contribute to the development of inflammatory and allergic diseases, cardiovascular disease and cancer. This PIR volume summarizes the physiological and pathophysiological functions of lipoxygenases.

Teaching Innovations in Lipid Science (Hardcover): Randall J Weselake Teaching Innovations in Lipid Science (Hardcover)
Randall J Weselake
R5,097 Discovery Miles 50 970 Ships in 12 - 17 working days

Featuring practical strategies and exciting experiments, Teaching Innovations in Lipid Science addresses lipid education at a range of levels from the novice to the graduate student and teacher. Peer-reviewed contributions from internationally known specialists, describe several methods and approaches designed to create new lipid courses, modify existing courses, and serve as a basis for pursuing novel avenues of instruction. Divided into two sections, the first focuses on teaching strategies and outlines some of the barriers that lipid science specialists face when transmitting accurate information. It emphasizes the development and implementation of creative programs that foster interest in lipid science, and presents novel problem-solving approaches. It discusses strategies for involving and evaluating independent study students and explains the successful use of sample cards to teach oilseed and cereal processing. This section also provides generalized accounts of biotechnology and crop improvement and isoprenoid biochemistry, including improvement of oilseed crops and tips on explaining DNA science and crop biotechnology. The second section begins with simple demonstrations on the physical properties of lipids suitable for middle- and high school students. It follows with more complex experiments on analyzing lipids in food oils, plasma, and milk utilizing thin layer chromatography, gas chromatography, and high performance liquid chromatography. Contributions include information on convenient enzyme test kits with exercises that can translate to a lab course beginning with chromatographic methods for lipid analysis. The final chapter presents theory and experiments for studying lipid metabolism in the plastid by describing preparation methods, studying metabolite uptake, and pathway analysis.

Structured and Modified Lipids (Hardcover, illustrated edition): Frank D. Gunstone Structured and Modified Lipids (Hardcover, illustrated edition)
Frank D. Gunstone
R8,662 Discovery Miles 86 620 Ships in 12 - 17 working days

This text addresses critical topics in the expanding market and production for lipids. It combines novel and traditional methods from technological and biological perspectives to achieve the most effective pathways for production of modified lipids. The book is organized into three sections exploring development, new production methods and successful products and uses.

Lipids in Plant and Algae Development (Hardcover, 1st ed. 2016): Yuki Nakamura, Yonghua Li-Beisson Lipids in Plant and Algae Development (Hardcover, 1st ed. 2016)
Yuki Nakamura, Yonghua Li-Beisson
R5,777 Discovery Miles 57 770 Ships in 10 - 15 working days

This book summarizes recent advances in understanding the functions of plant and algal lipids in photosynthesis, in development and signaling, and in industrial applications. As readers will discover, biochemistry, enzymology and analytical chemistry, as well as gene knock-out studies have all contributed to our rapidly increasing understanding of the functions of lipids. In the past few decades, distinct physical and biochemical properties of specific lipid classes were revealed in plant and algal lipids and the functional aspects of lipids in modulating critical biological processes have been uncovered. These chapters from international authors across relevant research fields highlight the underlying evolutionary context of lipid function in photosynthetic unicellular and multicellular organisms. The book goes on to encompass what lipids can do for industrial applications at a time of fascination with plants and algae in carbon fixation and as sources for production of food, energy and novel chemicals. The developmental context is a part of the fresh and engaging perspective that is presented in this work which graduate students and scientists will find both illuminating and useful.

Lipid Technologies and Applications (Hardcover): Fred B. Padley Lipid Technologies and Applications (Hardcover)
Fred B. Padley
R10,456 Discovery Miles 104 560 Ships in 12 - 17 working days

"Provides a comprehensive review of the major technologies and applications of lipids in food and nonfood uses, including current and future trends. Discusses the nature of lipids, their major sources, and role in nutrition."

Bioactive Lipid Mediators - Current Reviews and Protocols (Hardcover, 1st ed. 2015): Takehiko Yokomizo, Makoto Murakami Bioactive Lipid Mediators - Current Reviews and Protocols (Hardcover, 1st ed. 2015)
Takehiko Yokomizo, Makoto Murakami
R5,599 Discovery Miles 55 990 Ships in 12 - 17 working days

This book summarizes the most recent progress in the studies of lipid mediators from the molecular to clinical level and introduces newly created tools for analysis including imaging mass spectrometry. Comprising 29 chapters divided into four major parts, the book describes the molecular natures of enzymes, transporters, and receptors for lipid mediators (Part I), the function of lipid mediators in Drosophila and Zebrafish (Part II), the relationships between lipid mediators and various diseases (Part III), and detailed procedures of extraction, preparation, and quantification of lipid mediators (Part IV). Research on lipid mediators initially started with analysis of the action of aspirin, and subsequent biochemical experiments identified many enzymes and receptors responsible for the biosynthesis and signal transduction of individual lipid mediators. Through the phenotypic analyses of transgenic and knockout mice, it has been shown that the dysregulation of some lipid mediators causes inflammatory, immune, or oncogenic disorders. Lipid mediators have attracted increased attention because their structures are conserved among different species, and their biosynthetic and signaling pathways have been deciphered at the molecular level. Many drugs that target lipid mediators are already being used in hospitals, and this book suggests further possibilities for development of a wide variety of such drugs. Very recently, highly sensitive mass spectrometry has begun to be used to identify novel lipid mediators that are present only in trace amounts in tissues but with robust biological activity. Written by international experts, this book provides readers a comprehensive view of lipid mediators and related topics and helps in the process of determining research targets for the near future.

Advances in Planar Lipid Bilayers and Liposomes, Volume 8 (Hardcover, 6 Ed): A. Leitmannova Liu Advances in Planar Lipid Bilayers and Liposomes, Volume 8 (Hardcover, 6 Ed)
A. Leitmannova Liu
R4,986 Discovery Miles 49 860 Ships in 12 - 17 working days

"Advances in Planar Lipid Bilayers and Liposomes, " Volume 8, continues to include invited chapters on a broad range of topics, covering both main arrangements of the reconstituted system, namely planar lipid bilayers and spherical liposomes. The invited authors present the latest results in this exciting multidisciplinary field of their own research group.
Many of the contributors working in both fields over many decades were in close collaboration with the late Prof. H. Ti Tien, the founding editor of this book series. There are also chapters written by some of the younger generation of scientists included in this series. This volume keeps in mind the broader goal with both systems, planar lipid bilayers and spherical liposomes, which is the further development of this interdisciplinary field worldwide.
* Incorporates contributions from newcomers and established and experienced researchers
* Explores the planar lipid bilayer systems and spherical liposomes from both theoretical and experimental perspectives
* Serves as an indispensable source of information for new scientists

Phospholipid Technology and Applications (Hardcover): F.D. Gunstone Phospholipid Technology and Applications (Hardcover)
F.D. Gunstone
R3,909 Discovery Miles 39 090 Ships in 12 - 17 working days

Phospholipid technology and applications is an essential reference for technologists developing food and cosmetics products, scientists researching phospholipids in biological and food systems, technologists in fats and oils refining, and scientists developing drugs and drug delivery systems and carriers.
The major source of phospholipids is the lecithin recovered during degumming of vegetable oils, particularly soybean oil. This crude material finds uses in its own right but can be purified through a series of processes which eventually lead to individual phospholipid classes such as phosphatidylcholines.
It is widely accepted that oil and water do not mix but there are several areas in science and technology where these two distinct phases must coexist in stable emulsions. This is achieved by admixture of amphiphilic molecules of which the phospholipids are important natural examples. Today, phospholipids find many uses in the food industry and in other industries which exploit the amphiphilic nature of these compounds. Further, there are now important procedures by which their amphiphilicity can be optimized for different uses.
The early chapters in this book are devoted to the more common glycerol-based phospholipids and cover their structure, source, composition, modification by chemical and enzymatic methods, their physical, chemical, and nutritional properties, and their major uses. The final chapter is devoted to another kind of phospholipid, the sphingolipids, in which there is a growing interest.

Advances in Planar Lipid Bilayers and Liposomes, Volume 6 (Hardcover, 6th edition): A. Leitmannova Liu Advances in Planar Lipid Bilayers and Liposomes, Volume 6 (Hardcover, 6th edition)
A. Leitmannova Liu
R4,981 Discovery Miles 49 810 Ships in 12 - 17 working days

Advances in Planar Lipid Bilayers and Liposomes, Volume 6, continues to include invited chapters on a broad range of topics, covering both main arrangements of the reconstituted system, namely planar lipid bilayers and spherical liposomes. The invited authors present the latest results in this exciting multidisciplinary field of their own research group.
Many of the contributors working in both fields over many decades were in close collaboration with the late Prof. H. Ti Tien, the founding editor of this book series. There are also chapters written by some of the younger generation of scientists included in this series. This volume keeps in mind the broader goal with both systems, planar lipid bilayers and spherical liposomes, which is the
further development of this interdisciplinary field worldwide.
* Contributions from newcomers and established and experienced researchers
* Exploring theoretically and experimentally the planar lipid bilayer systems and spherical liposomes
* This volume is dedicated to mark the Bilayer Lipid Membranes 45th anniversary

Lipid Oxidation (Hardcover, 2nd edition): E N Frankel Lipid Oxidation (Hardcover, 2nd edition)
E N Frankel
R4,652 Discovery Miles 46 520 Ships in 12 - 17 working days

In this second edition, Edwin Frankel has updated and extended his now well-known book Lipid oxidation which has come to be regarded as the standard work on the subject since the publication of the first edition seven years previously. His main objective is to develop the background necessary for a better understanding of what factors should be considered, and what methods and lipid systems should be employed, to achieve suitable evaluation and control of lipid oxidation in complex foods and biological systems.
The oxidation of unsaturated fatty acids is one of the most fundamental reactions in lipid chemistry. When unsaturated lipids are exposed to air, the complex, volatile oxidation compounds that are formed cause rancidity. This decreases the quality of foods that contain natural lipid components as well as foods in which oils are used as ingredients. Furthermore, products of lipid oxidation have been implicated in many vital biological reactions, and evidence has accumulated to show that free radicals and reactive oxygen species participate in tissue injuries and in degenerative disease.
Although there have been many significant advances in this challenging field, many important problems remain unsolved. This second edition of Lipid oxidation follows the example of the first edition in offering a summary of the many unsolved problems that need further research. The need to understand lipid oxidation is greater than ever with the increased interest in long-chain polyunsaturated fatty acids, the reformulation of oils to avoid hydrogenation and trans fatty acids, and the enormous attention given to natural phenolic antioxidants, including flavonoids and other phytochemicals.

Handbook of Biochemistry and Molecular Biology - Lipids Carbohydrates, Steroids (Paperback, 3rd edition): Gerald D. Fasman Handbook of Biochemistry and Molecular Biology - Lipids Carbohydrates, Steroids (Paperback, 3rd edition)
Gerald D. Fasman
R1,989 Discovery Miles 19 890 Ships in 12 - 17 working days

Published in 1975: This volume contains the completed section of the Handbook of Biochemistry and Molecular Biology with data pertaining to Lipids, Carbohydrates, and Steroids.

The Role of Bioactive Lipids in Cancer, Inflammation and Related Diseases (Hardcover, 1st ed. 2019): Kenneth V. Honn, Darryl C.... The Role of Bioactive Lipids in Cancer, Inflammation and Related Diseases (Hardcover, 1st ed. 2019)
Kenneth V. Honn, Darryl C. Zeldin
R3,671 Discovery Miles 36 710 Ships in 12 - 17 working days

The Organizing Committee of the 15th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases compiled a group of junior investigators to provide reviews on the topics they presented at the Puerto Vallarta Bioactive Lipids conference, as part of the book series, Advances in Experimental Medicine and Biology (AEMB). The book in this series will be titled Bioactive Lipids in Cancer, Inflammation and Related Diseases. Topics range from all classes of lipids including prostaglandins, resolvins, spingolipids, P450-derived lipids, endocannabanoids and phospholipids. The focus includes physiology, cell biology, and structural studies in organisms from bacteria to humans and how these studies addressed the role of lipids in various disease i.e. cancer, inflammation, diabetes, obesity, cardiovascular disease and others.

Teaching Innovations in Lipid Science (Paperback): Randall J Weselake Teaching Innovations in Lipid Science (Paperback)
Randall J Weselake
R1,859 Discovery Miles 18 590 Ships in 12 - 17 working days

Featuring practical strategies and exciting experiments, Teaching Innovations in Lipid Science addresses lipid education at a range of levels from the novice to the graduate student and teacher. Peer-reviewed contributions from internationally known specialists, describe several methods and approaches designed to create new lipid courses, modify existing courses, and serve as a basis for pursuing novel avenues of instruction. Divided into two sections, the first focuses on teaching strategies and outlines some of the barriers that lipid science specialists face when transmitting accurate information. It emphasizes the development and implementation of creative programs that foster interest in lipid science, and presents novel problem-solving approaches. It discusses strategies for involving and evaluating independent study students and explains the successful use of sample cards to teach oilseed and cereal processing. This section also provides generalized accounts of biotechnology and crop improvement and isoprenoid biochemistry, including improvement of oilseed crops and tips on explaining DNA science and crop biotechnology. The second section begins with simple demonstrations on the physical properties of lipids suitable for middle- and high school students. It follows with more complex experiments on analyzing lipids in food oils, plasma, and milk utilizing thin layer chromatography, gas chromatography, and high performance liquid chromatography. Contributions include information on convenient enzyme test kits with exercises that can translate to a lab course beginning with chromatographic methods for lipid analysis. The final chapter presents theory and experiments for studying lipid metabolism in the plastid by describing preparation methods, studying metabolite uptake, and pathway analysis.

Phosphatidate Phosphohydrolase (1988) - Volume II (Paperback): David N. Brindley Phosphatidate Phosphohydrolase (1988) - Volume II (Paperback)
David N. Brindley
R984 R829 Discovery Miles 8 290 Save R155 (16%) Ships in 12 - 17 working days

Each of these chapters has a general section that describes the special needs for glycerolipid synthesis and the physiological context in which the regulation of phosphatidate phosphohydrolase activity can be understood.

Phosphatidate Phosphohydrolase (1988) - Volume I (Paperback): David N. Brindley Phosphatidate Phosphohydrolase (1988) - Volume I (Paperback)
David N. Brindley
R969 R814 Discovery Miles 8 140 Save R155 (16%) Ships in 12 - 17 working days

Each of these chapters has a general section that describes the special needs for glycerolipid synthesis and the physiological context in which the regulation of phosphatidate phosphohydrolase activity can be understood.

Bioactive Ceramides in Health and Disease - Intertwined Roles of Enigmatic Lipids (Hardcover, 1st ed. 2019): Johnny Stiban Bioactive Ceramides in Health and Disease - Intertwined Roles of Enigmatic Lipids (Hardcover, 1st ed. 2019)
Johnny Stiban
R2,933 Discovery Miles 29 330 Ships in 10 - 15 working days

This book is about the various roles of bioactive ceramides and other sphingolipids in cellular biology. The enigmatic biophysical and biochemical properties of ceramides and their propensity to influence membranes whether as rafts or protein-permeable channels are heavily discussed. Metabolism of ceramides and their metabolites is also focused with ceramide synthase family of proteins being a target of extensive review. Ceramide 1-phosphate and other sphingolipids are also presented in cellular physiology and pathophysiology. Prokaryotic origins of mitochondria at the level of membranes and the occurrence of apoptosis in bacteria are presented. Many aspects of ceramide and sphingolipid biology are addressed in this book. Its focus is the metabolism of ceramide in normal and diseased states and the biophysical and biochemical mechanisms governing the bioactivity of these molecules. Sphingolipid research has surged over the past thirty years and this book gathers the recent findings of various aspects of sphingolipid biochemistry. World-renowned scientists from the field of lipid biology, specifically sphingolipid biochemistry, were gathered to write this book. Scholars from most continents of the globe committed to write diligently about their expertise and the newest findings in the relevant fields. This book came to fruition after almost a year and a half of laborious preparation and diligent writings. This book is targeted to the experienced reader who is looking to read about the various aspects of bioactive ceramide signaling, as well as to the newcomer into the field, as the topics are explained in concise yet very informative manner. The authors and editor wish all readers a pleasant time reading this volume, and are adamant that this book will meet all expectations.

Handbook of Biochemistry and Molecular Biology - Lipids Carbohydrates, Steroids (Hardcover, 3rd edition): Gerald D. Fasman Handbook of Biochemistry and Molecular Biology - Lipids Carbohydrates, Steroids (Hardcover, 3rd edition)
Gerald D. Fasman
R6,018 Discovery Miles 60 180 Ships in 12 - 17 working days

Published in 1975: This volume contains the completed section of the Handbook of Biochemistry and Molecular Biology with data pertaining to Lipids, Carbohydrates, and Steroids.

Biochemistry and Function of Sterols (Hardcover): W.David Nes, Edward J. Parish Biochemistry and Function of Sterols (Hardcover)
W.David Nes, Edward J. Parish
R6,124 Discovery Miles 61 240 Ships in 12 - 17 working days

Leading international scientists bring current and developing topics in sterol research together in Biochemistry and Function of Sterols. The authors are experts in each major area of sterol research-medicine, biochemistry, chemistry, and agriculture. Each chapter features the current state of research as well as new and developing research topics. Throughout the volume the focus is on the major and expanding areas of sterol biochemistry and function of sterols in all classes or organisms. The broad scope of this work embraces many disciplines and will be of interest to a variety of researchers, students, and lay people. Professors will find Biochemistry and Function of Sterols an excellent choice as a textbook for courses on steroid, lipid, or plant biochemistry.

Lipid Analysis (Paperback): Prof F W Hemming, J.N. Hawthorne Lipid Analysis (Paperback)
Prof F W Hemming, J.N. Hawthorne
R750 Discovery Miles 7 500 Ships in 10 - 15 working days

There is increasing recognition of the diversity and biological importance of lipids. Lipid modifications of other biological molecules are now also the subject of intense research activity. This 'user-friendly' introduction describes the techniques curre

Handbook of Lipids in Human Nutrition (Hardcover): Gene A. Spiller Handbook of Lipids in Human Nutrition (Hardcover)
Gene A. Spiller
R5,680 Discovery Miles 56 800 Ships in 12 - 17 working days

The Handbook of Lipids in Human Nutrition is a concise reference for professionals and students interested in the role of lipids in nutrition. Over 100 tables and illustrations provide quick access to the most current data available.

Stealth Liposomes (Hardcover): Danilo D. Lasic, Francis J. Martin Stealth Liposomes (Hardcover)
Danilo D. Lasic, Francis J. Martin
R11,114 Discovery Miles 111 140 Ships in 12 - 17 working days

This book examines stealth liposomes from a multidisciplinary approach, which includes theoretical polymer physics, organic synthesis, colloid science, and biology. Discussions include theory, chemistry, biochemistry, pharmacology, preclinical studies in model systems, and medical applications in humans.

Permeability and Stability of Lipid Bilayers (Hardcover): Sidney A. Simon Permeability and Stability of Lipid Bilayers (Hardcover)
Sidney A. Simon; Contributions by OLE G. Mouritsen, David Needham, David S. Cafiso, Larry S. Liebovitch, …
R8,911 Discovery Miles 89 110 Ships in 12 - 17 working days

This book presents a comprehensive and coherent picture of how molecules diffuse across a liquid that is, on average, only two molecules thick. It begins by characterizing bilayers structurally, using X-ray diffraction, and then mechanically by measuring elastic moduli and mechanisms of failure. Emphasis is placed on the stability and mechanical properties of plant membranes that are subject to very large osmotic and thermal stresses. Using this information, the transport of molecules of increasing complexity across bilayers is analyzed.

Liposomes, Lipid Bilayers and Model Membranes - From Basic Research to Application (Hardcover): Georg Pabst, Mu-Ping Nieh, John... Liposomes, Lipid Bilayers and Model Membranes - From Basic Research to Application (Hardcover)
Georg Pabst, Mu-Ping Nieh, John Katsaras, Norbert Kucerka
R5,417 Discovery Miles 54 170 Ships in 12 - 17 working days

As a result of their unique physical properties, biological membrane mimetics, such as liposomes, are used in a broad range of scientific and technological applications. Liposomes, Lipid Bilayers and Model Membranes: From Basic Research to Application describes state-of-the-art research and future directions in the field of membranes, which has evolved from basic studies of the physicochemical properties of amphiphiles to their application in industry and medicine. Written by leading researchers in their fields, this book describes basic and applied research, and serves as a useful reference for both the novice and the expert. Part one covers a range of basic research topics, from theory and computational simulations to some of the most up-to-date experimental research. Topics discussed include soft matter physics of membranes, nonlamellar phases, extraction of molecules by amphiphiles, lipid models for membrane rafts, membrane dynamics, nanodiscs, microemulsions, active membranes, as well as interactions of bilayers with drugs or DNA to treat disease or for gene transfer, respectively. Part two of the book focuses on technological applications of amphiphiles, such as liposome-based nanoparticles for drug delivery, formulation of liposomes for prolonged in vivo circulation and functionalization for medical purposes, novel drug delivery systems for increased drug loading, and the use of tethered membranes for bio-sensing applications. Chapters also describe the use of liposomes in textile dyeing and how lipidic nanoparticles are used by the food industry.

Handbook of Lipid Bilayers (Hardcover, 2nd edition): Derek Marsh Handbook of Lipid Bilayers (Hardcover, 2nd edition)
Derek Marsh
R8,451 Discovery Miles 84 510 Ships in 12 - 17 working days

Now in its second edition, the Handbook of Lipid Bilayers is a groundbreaking work that remains the field's definitive text and only comprehensive source for primary physicochemical data relating to phospholipid bilayers. Along with basic thermodynamic data, coverage includes both dynamic and structural properties of phospholipid bilayers. It is an indispensable reference for users of bilayer model membranes and liposome delivery systems and for those interested in the biophysics of membrane structure. Each chapter in the second edition contains considerable amounts of explanation and elaboration, including, in many cases, extensive analysis of structural connections between the data. New in the Second Edition: Chapters on crystal structures of phospholipids include new structures and more comprehensive data on bond lengths, bond angles, and torsion angles-and all coordinates are Cartesian Wide-angle data is indexed whenever possible to characterize chain-packing modes in gel and crystalline lamellar phases Low-angle data are analyzed in terms of the lipid and water thicknesses Headgroup separations in electron density profiles for phospholipids are included, and a separate section is devoted to the in-depth analysis of electron density profiles that provides the most detailed structural information on fluid lamellar phases Phase diagrams of phospholipid mixtures are vastly expanded and have been redrawn in standardized format to aid intercomparison. Cholesterol, including ternary systems, is now featured. New sections on titration calorimetry, and much extended data on the temperature dependence of transfer rates The greatly expanded chapter on bilayer-bilayer interactions features new and detailed information on the components of interbilayer pressures

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