I first became interested in prolactin a little over two years ago.
I was then working in Nairobi and I knew nothing about the hormone
apart from its role in lactation. Professor Mohammed Hyder of the
Department of Zoology in the University of Nairobi was interested
in the endocrine mechanisms which enable Tilapia fish to adapt to
water with a very high electrolyte content. He invited me to a
seminar given by Professor Howard Bern which was largely concerned
with the role prolactin plays in fluid and electrolyte balance in
sub-mammalian vertebrates. This inspired me to begin a programme of
research into the roles prolactin plays in man and other animals.
Very few physiologists or clinicians seem aware of the multifarious
effects of prolactin in mammals. This book therefore aims to give a
comprehensive account of the mammalian physiology of prolactin and
to make suggestions about its possible role in diseases ranging
from cancer to mental illness. The two subjects which have been
previously widely covered, the roles of prolactin in lactation and
in rat mammary cancer, are presented relatively briefly though with
a full list of references. Other subjects are dealt with more
extenSively and I hope that many research workers and clinicians
may find the book helpful.
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