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Schizophrenia Research Progress (Hardcover)
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Schizophrenia Research Progress (Hardcover)
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Schizophrenia is a chronic, severe, and disabling psychosis, which
is an impairment of thinking in which the interpretation of reality
is abnormal. Psychosis is a symptom of a disordered brain.
Approximately 1 percent of the population world-wide develops
schizophrenia during their lifetime. Although schizophrenia affects
men and women with equal frequency, the disorder often appears
earlier in men, usually in the late teens or early twenties, than
in women, who are generally affected in the twenties to early
thirties. People with schizophrenia often suffer symptoms such as
hearing internal voices not heard by others, or believing that
other people are reading their minds, controlling their thoughts,
or plotting to harm them. The current evidence concerning the
causes of schizophrenia is a mosaic. It is quite clear that
multiple factors are involved. These include changes in the
chemistry of the brain, changes in the structure of the brain, and
genetic factors. Viral infections and head injuries may also play a
role. New molecular tools and modern statistical analyses allow
focusing in on particular genes that might make people more
susceptible to schizophrenia by affecting, for example, brain
development or neurotransmitter systems governing brain
functioning. State-of-the-art imaging techniques are being used to
study the living brain. They have recently revealed specific,
subtle abnormalities in the structure and function of the brains of
patients with schizophrenia. In other imaging studies, early
biochemical changes that may precede the onset of disease symptoms
have been noted, prompting examination of the neural circuits that
are most likely to be involved in producing those symptoms. This
book presents new and important research in the field.
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