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Endocrine Disruption in Fish (Hardcover, 1998 ed.)
Loot Price: R3,276
Discovery Miles 32 760
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Endocrine Disruption in Fish (Hardcover, 1998 ed.)
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There is increasing concern in the media, among politicians and
within environmental organizations, about the effects of chemicals
in our environment that affect the endocrine systems of wildlife
and humans. At its simplest these are referred to as
gender-bending' chemicals or environmental estrogens'. The
chemicals in question (pesticides, PCBs, plasticizers,
petrochemicals, and a variety of industrial chemicals) have been
known to decrease human sperm counts, cause fish to change sex',
and increase male genital abnormalities. A great deal of pressure
has been placed on environmental protection agencies to devise
regulatory tests for the effects of these chemicals and to require
limitations on their manufacture and release. Fish are increasingly
recognized as an excellent model for such tests, in that the
aquatic environment may provide early warnings of the effects that
these chemicals will have on human health. In addition, the large
number of eggs which fish produce provides an excellent model to
examine the effects on female fertility. Endocrine Disruption in
Fish provides a simple yet extensive background to the field of
fish endocrinology in order to assist those toxicologists who have
a limited background in either mammalian or fish endocrinology. It
shows that environmental estrogens do not simply affect male
reproductive potential, but that they may equally well affect the
female. It is possible that these chemicals may have a complex
effect on the brain, hypothalamus, pituitary, gonad and liver of
both sexes. There are many other chemicals which affect both the
gonads and other parts of the endocrine system to cause decreased
fertility, abnormal sexual differentiation andbehavior, decreased
response to stress, immune deficiency or altered basal metabolism.
Many thousand man-made chemicals are released into the environment,
but very few have been tested for endocrine disrupting activity.
This book covers only the minute fraction for which evidence has
been collected.
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