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Genetic Manipulation of the Nervous System (Hardcover)
Loot Price: R2,250
Discovery Miles 22 500
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Genetic Manipulation of the Nervous System (Hardcover)
Series: Neuroscience Perspectives
Expected to ship within 12 - 17 working days
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Neuroscience Perspectives provides multidisciplinary reviews of
topics in one of the most diverse and rapidly advancing fields in
the life sciences.
Whether you are a new recruit to neuroscience, or an established
expert, look to this series for 'one-stop' sources of the
historical, physiological, pharmacological, biochemical, molecular
biological and therapeutic aspects of chosen research areas.
The recent development of Gene Therapy procedures which allow
specific genes to be delivered to human patients who lack
functional copies of them is of major therapeutic importance. In
addition such gene delivery methods can be used in other organisms
to define the function of particular genes. These studies are of
particular interest in the nervous system where there are many
incurable diseases like Alzheimer's and Parkinson's diseases which
may benefit from therapies of this kind. Unfortunately gene
delivery methods for use in the nervous system have lagged behind
those in other systems due to the fact that the methods developed
in other systems are often not applicable to cells like neurons
which do not divide. This book discusses a wide range of methods
which have now been developed to overcome these problems and allow
safe and efficient delivery of particular genes to the brain.
Methods discussed include virological methods, physical methods
(such as liposomes) and the transplantation of genetically modified
cells. In a single volume therefore this book provides a complete
view of these methods and indicates how they can be applied to the
development of therapies for treating previously incurable
neurological disorders.
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