THE MOST PRACTICAL, UP-TO-DATE GUIDE TO MODELLING AND ANALYZING
TIME-TO-EVENT DATA--NOW IN A VALUABLE NEW EDITION
Since publication of the first edition nearly a decade ago,
analyses using time-to-event methods have increase considerably in
all areas of scientific inquiry mainly as a result of
model-building methods available in modern statistical software
packages. However, there has been minimal coverage in the available
literature to9 guide researchers, practitioners, and students who
wish to apply these methods to health-related areas of study.
Applied Survival Analysis, Second Edition provides a comprehensive
and up-to-date introduction to regression modeling for
time-to-event data in medical, epidemiological, biostatistical, and
other health-related research.
This book places a unique emphasis on the practical and
contemporary applications of regression modeling rather than the
mathematical theory. It offers a clear and accessible presentation
of modern modeling techniques supplemented with real-world examples
and case studies. Key topics covered include: variable selection,
identification of the scale of continuous covariates, the role of
interactions in the model, assessment of fit and model assumptions,
regression diagnostics, recurrent event models, frailty models,
additive models, competing risk models, and missing data.
Features of the Second Edition include: Expanded coverage of
interactions and the covariate-adjusted survival functionsThe use
of the Worchester Heart Attack Study as the main modeling data set
for illustrating discussed concepts and techniquesNew discussion of
variable selection with multivariable fractional polynomialsFurther
exploration of time-varying covariates, complex with
examplesAdditional treatment of the exponential, Weibull, and
log-logistic parametric regression modelsIncreased emphasis on
interpreting and using results as well as utilizing multiple
imputation methods to analyze data with missing valuesNew examples
and exercises at the end of each chapter
Analyses throughout the text are performed using Stata(R)
Version 9, and an accompanying FTP site contains the data sets used
in the book. Applied Survival Analysis, Second Edition is an ideal
book for graduate-level courses in biostatistics, statistics, and
epidemiologic methods. It also serves as a valuable reference for
practitioners and researchers in any health-related field or for
professionals in insurance and government.
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