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Allicin - The Natural Sulfur Compound from Garlic with Many Uses (Hardcover)
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Allicin - The Natural Sulfur Compound from Garlic with Many Uses (Hardcover)
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Allicin is the major active sulfur-containing moiety that is
released when garlic cloves are crushed or damaged. Since its first
recorded use in ancient times to ward off snakebites and by the
physician Hippocrates to treat pneumonia and heal wounds, allicin
has come a long way and its attributes now include antimicrobial
and anti-insecticidal activities. Given the rapid appearance of
resistant microbes and insects, allicin clearly has merit in these
spheres, even more so as resistance does not appear following its
usage. More recently allicin has been successfully used as a
complementary treatment for chronic inflammatory diseases, which
include type II diabetes, cardiovascular disease and even certain
tumors. Having a "natural" medicine, which is associated with an
absence of side effects, can only be beneficial in conditions
requiring long-term usage and it is clear that allicin's potential
as an individual or adjunct medicine needs to be evaluated. The
gold standard for phase III human studies are double blind
randomized placebo controlled trials and allicin's success in this
area is just beginning to be realized. Allicin has great potential,
and maximizing its bioavailability could be enhanced using
computational chemistry methodology combined with the stabilization
methods already used for other phytomedicines, such as curcumin.
Given the attention it deserves, it is likely that allicin will
provide much needed alternative management strategies for
decreasing infection and disease over the next decade.
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