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Human in Vitro Fertilization and Embryo Transfer (Paperback, Softcover reprint of the original 1st ed. 1984)
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Discovery Miles 16 230
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Human in Vitro Fertilization and Embryo Transfer (Paperback, Softcover reprint of the original 1st ed. 1984)
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The births of more than 100 apparently normal infants at term
following pregnancies initiated by in vitro fertilization and
embryo transfer testifies to the successful clinical application of
insights obtained from studies in reproductive biology over the
last 20 years. In women, these studies have included: 1)
characterization of the changes in blood hormone profiles
throughout ovulatory menstrual cycles; 2) documentation of the
hormonal composition of antral fluid in developing and degenerating
preovulatory follicles; 3) correlation of these observations with
the state of oocyte maturation and the fertilizability of the
oocyte; 4) application of pharmacologic agents for perturbing the
normal hormone profiles to regulate the number of preovulatory
follicles developing and the time of ovulation; and 5) development
of non-invasi ve methods for monitoring follicular development.
Optimizing methods for maturing and fertilizing eggs, for moni
toring normal development in vi tro, and for transferring and
achieving implantation of embryos are continuing concerns of
physicians and scientists responsible for extant programs. In
addition, all serious students of reproductive biology should
critically examine every facet of the processes which must
concatenate to assure birth of normal infants following pregnancies
achieved by these methods. However, the literature which contains
the informational substrate is dispersed widely in a plethora of
journals not always readily accessible. Bringing the essentials
together facilitates both rapid retrieval of data and access to
relevant literature.
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