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Statistical Methods in Environmental Epidemiology (Hardcover)
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Statistical Methods in Environmental Epidemiology (Hardcover)
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Environmental epidemiology is the study of the environmental causes
of disease in populations and how these risks vary in relation to
intensity and duration of exposure and other factors like genetic
susceptibility. As such, it is the basic science upon which
governmental safety standards and compensation policies for
environmental and occupational exposure are based. Profusely
illustrated with examples from the epidemiologic literature on
ionizing radiation and air ollution, this text provides a
systematic treatment of the statistical challenges that arise in
environmental health studies and the use of epidemiologic data in
formulating public policy, at a level suitable for graduate
students and epidemiologic researchers.
After a general overview of study design and statistical methods
for epidemiology generally, the book goes on to address the
problems that are unique to environmental health studies,
special-purpose designs like two-phase case-control studies and
countermatching, statistical methods for modeling
exposure-time-response relationships, longitudinal and time-series
studies, spatial and ecologic methods, exposure measurement error,
interactions, and mechanistic models. It also discusses studies
aimed at evaluating the public health benefits of interventions to
improve the environment, the use of epidemiologic data to establish
environmental safety standards and compensation policy, and
concludes with emerging problems in reproductive epidemiology,
natural and man-made disasters like global warming, and the global
burden of environmentally caused disease. No other book provides
such a broad perspective on the methodological challenges in this
field at a level accessible to both epidemiologists and
statisticians.
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