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Recent Progress in Atherosclerosis Research (Paperback, Softcover reprint of the original 1st ed. 1993)
Loot Price: R2,951
Discovery Miles 29 510
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Recent Progress in Atherosclerosis Research (Paperback, Softcover reprint of the original 1st ed. 1993)
Series: Current Topics in Pathology, 87
Expected to ship within 10 - 15 working days
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During the past years a considerable number of books have been
published on atherosclerosis research. Much attention has been
focused on the biochemical properties of lipoproteins and the
involvement of lipoprotein metabolism in the atherogenic process.
The monograph presented here focuses on morphologic studies of
atherosclerotic plaque. One chapter deals with the pathobiochemical
changes in the arterial wall at the inception of atherosclerosis.
Recently the specific role of macro phages in atherogenesis has
been the object of much interest. A morphological study of their
role and differentiation is the topic of another chapter. This is
complemented by a study of lipoprotein receptors on macrophages and
smooth muscle cells both in cell culture and in situ, based on
electron microscopic investiga- tions. An immunohistological study
on the in situ localization promotes our understanding
oflipoprotein metabolism in the arterial wall. The morphologic
aspects of more advanced lesions are present- ed in studies of
collagens and angiogenic processes in the athero- sclerotic vessel
wall. Experimental investigations have also been useful for
understanding the pathogenetic aspects of atherosclerosis; one
crrapter concentrates on the metabolism of fibromuscular and
atheromatous plaques in an experimental model. A final chapter
deals with transplant arteriopathy and its possible parallels with
conventional atherosclerosis. The widespread discussion of athero-
genesis is focused on the arterial wall and its morphological
alter- ations, emphasizing once again the importance of
morphological research for understanding the pathological basis of
disease. Borstel and Magdeburg E. VOLLMER and A.
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