This book was first published in 2002. It presents an overview of
ethnic and racial differences in response to medications and offers
insight into the genetic and non-genetic reasons for these
differences. The roles of pharmacogenomics and pharmacogenetics in
drug development, regulatory aspects of representing minorities in
clinical trials, as well as NIH, ICH and FDA guidelines as they
pertain to these issues are examined in detail. Finally, various
strategies to increase recruitment and retention of minority
populations in clinical trials are considered.
General
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