Molecular Aspects of Oxidative Drug Metabolizing Enzymes - Their Significance in Environmental Toxicology, Chemical Carcinogenesis and Health (Paperback, Softcover reprint of the original 1st ed. 1995)

Presented here are recent advances in biochemical, toxicological, and regulatory aspects of oxidative drug metabolizing enzymes. Mainly cytochrome P450-dependent and flavin-containing monooxygenases (FMO) are covered. Moreover, the book deals with genotoxicity studies and toxicological interactions of environmental chemicals and mechanisms of mutagenicity and tumor formation. The construction of genetically engineered mammalian cells for the production of a specific P450 isozyme and the application of these cell lines in drug metabolism, mutagenicity and toxicity studies are described in detail. Further, insight is provided into how a number of aquatic species cope with pollutants and their genotoxicity.

General

Imprint:	Springer-Verlag
Country of origin:	Germany
Series:	Nato ASI Subseries H:, 90
Release date:	December 2011
First published:	1995
Editors:	Emel Arinc • John B. Schenkman • Ernest Hodgson
Dimensions:	235 x 155 x 32mm (L x W x T)
Format:	Paperback
Pages:	614
Edition:	Softcover reprint of the original 1st ed. 1995
ISBN-13:	978-3-642-79530-5
Categories:	Books > Medicine > Other branches of medicine > Pharmacology > General Books > Science & Mathematics > Biology, life sciences > Biochemistry > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	3-642-79530-7
Barcode:	9783642795305

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