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Books > Medicine > Clinical & internal medicine > Cardiovascular medicine
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Adverse Cutaneous Drug Reactions to Cardiovascular Drugs (Hardcover, 2014 ed.)
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Adverse Cutaneous Drug Reactions to Cardiovascular Drugs (Hardcover, 2014 ed.)
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Adverse cutaneous drug reactions (ACDR) are among the most frequent
events in patients receiving drug therapy. Cardiovascular (CV)
drugs are an important group of drugs with potential risk of
developing ACDR especially in elderly as marketing of more new
drugs and their prescription continue to increase. However, like
with most other drugs the exact incidence of cutaneous side effects
from CV drugs is difficult to estimate due to sporadic reporting.
Moreover, a reliable designation of a certain drug as the cause of
a certain type of reaction can rarely be made. Apart from the
well-known angioedema/urticaria from ACE inhibitors, lichen planus
/ lichenoid reaction from beta adrenergic blockers and
photosensitivity from thiazid diuretics, ACDR from CV drugs might
be seen in a wide spectrum extending to rare but life-threatening
conditions such as erythroderma, Stevens-Johnson syndrome, toxic
epidermal necrolysis or drug hypersensitivity syndrome. In this
comprehensive review, the reported types of ACDR to CV drugs will
be discussed according to drug class and the type of dermatologic
reaction with special emphasize on cross-reactions and the role of
patch testing in diagnosis.
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