The Geometry of Population Genetics (Paperback, Softcover reprint of the original 1st ed. 1979)

The differential equations which model the action of selection and recombination are nonlinear equations which are impossible to It is even difficult to describe in general the solve explicitly. Recently, Shahshahani began using qualitative behavior of solutions. differential geometry to study these equations [28]. with this mono graph I hope to show that his ideas illuminate many aspects of pop ulation genetics. Among these are his proof and clarification of Fisher's Fundamental Theorem of Natural Selection and Kimura's Maximum Principle and also the effect of recombination on entropy. We also discover the relationship between two classic measures of 2 genetic distance: the x measure and the arc-cosine measure. There are two large applications. The first is a precise definition of the biological concept of degree of epistasis which applies to general (i.e. frequency dependent) forms of selection. The second is the unexpected appearance of cycling. We show that cycles can occur in the two-locus-two-allele model of selection plus recombination even when the fitness numbers are constant (i.e. no frequency dependence). This work is addressed to two different kinds of readers which accounts for its mode of organization. For the biologist, Chapter I contains a description of the entire work with brief indications of a proof for the harder results. I imagine a reader with some familiarity with linear algebra and systems of differential equations. Ideal background is Hirsch and Smale's text [15].

General

Imprint:	Springer-Verlag
Country of origin:	Germany
Series:	Lecture Notes in Biomathematics, 31
Release date:	November 1979
First published:	1979
Authors:	Ethan Akin
Dimensions:	244 x 170 x 11mm (L x W x T)
Format:	Paperback
Pages:	208
Edition:	Softcover reprint of the original 1st ed. 1979
ISBN-13:	978-3-540-09711-2
Categories:	Books > Science & Mathematics > Mathematics > Geometry > Differential & Riemannian geometry Books > Science & Mathematics > Mathematics > Applied mathematics > Mathematics for scientists & engineers
LSN:	3-540-09711-2
Barcode:	9783540097112

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