Evaluating the potential threat posed by advances in biotechnology,
especially genetically modified organisms (GMOs), and synthetic
biology remains a contentious issue. The rapid development of the
tools of molecular biology and metabolic engineering has enabled
the development of chimeric organisms which possess characteristics
which are not native to the wild variant. This is commonplace in
the area of biomanufacturing, where genes are introduced into
organisms such as E coli and products manufactured via large-scale
fermentation. More recently, entire metabolic pathways, albeit of
limited complexity, have been engineered into organisms, for
example, for the production of artemisinin in yeast.2 In addition
to such metabolic engineering projects, whole genomes are being
sequenced, leading to the possibility of creating organisms de
novo.
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