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Inborn Errors of Immunity and Phagocytosis - Monograph based upon Proceedings of the Fifteenth Symposium of The Society for the Study of Inborn Errors of Metabolism (Paperback, Softcover reprint of the original 1st ed. 1979)
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Discovery Miles 15 740
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Inborn Errors of Immunity and Phagocytosis - Monograph based upon Proceedings of the Fifteenth Symposium of The Society for the Study of Inborn Errors of Metabolism (Paperback, Softcover reprint of the original 1st ed. 1979)
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The rapid growth of immunology has greatly increased our
understanding of disease; this growth has also generated a subject
which at times appears separated from some of the basic medical
sciences. Recent studies in the areas of purine metabolism and of
polymorphonuclear neutrophil phago cyte function have, however,
linked immunology and clinical medicine with biochemistry. The
precise defects of the inborn errors of metabolism have now
provided good evidence for the importance of purine metabolism
specifically the enzymes adenosine deaminase and nucleoside
phosphorylase in lymphocyte function. In view of this and the
steady advance of clinical and biochemical investigation of the
polymorphonuclear neutrophil phago cyte, it appeared timely to
review the inborn errors of immunity and phagocytosis at the
fifteenth annual symposium of the Society for the Study of Inborn
Errors of Metabolism at Elsinore, Denmark on September II-14th, I
77. The papers presented at that meeting form the basis of this
volume which brings together contributions from immunologists,
biochemists and clinicians. This interdisciplinary communication
should be helpful to those concerned with immune function in their
patients or in the laboratory. The book is divided into four
sections, One: defects of cell-mediated immunity, Two: enzyme
defects and immunodeficiency, Three: disorders of non-specific
immunity and Four: screening for immunodeficiency. Section One
contains two reviews, one on immunodeficiency from Robert Good's
group in New York and another on the genetics of the immune system
from Arne Svejgaard of Copenhagen."
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