This important reference provides up-to-date information on all
aspects of ribosome-inactivating proteins (RIPs). Including a list
of all known RIPs, their distribution in nature, structure,
genetics and chemical and immunological properties, this reference
covers mechanisms of action, including the enzymatic activity on
various polynucleotide substrates; the interaction with, and entry
into cells; the toxicity to animals, including the pathology of
poisoning; and the immunomodulatory and allergenic activity. The
book further emphasizes the use of immunotoxins and other
conjugates in clinical trials for the therapy of cancer and
intractable pain.
General
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