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Biosynthesis - Aromatic Polyketides, Isoprenoids, Alkaloids (Hardcover, 2000 ed.)
Loot Price: R8,308
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Biosynthesis - Aromatic Polyketides, Isoprenoids, Alkaloids (Hardcover, 2000 ed.)
Series: Topics in Current Chemistry, 209
Expected to ship within 10 - 15 working days
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This book is the second of two volumes that deal with discovery of
chemical pathways of biosynthesis of natural products (secondary
metabolites). The first volume covered the use of isotopes in
biosynthetic research and the formation of enzyme cofactors and
reduced polyketides. This second volume describes biosynthesis of
aromatic (unreduced) polyketides, enzymes responsible for
cyclization of terpenoids (isoprenoids), and biochemical generation
of selected classes of alkaloids (prenylated tryptophan, tropane,
pyrrolizidine). Knowledge of the pathways and the techniques to
elucidate them opens the door to combinatorial biosynthesis as well
as to the production of targeted pharmaceutical agents utilizing a
combination of chemistry, molecular biology and protein
biochemistry.
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