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Vertebrate Development - Maternal to Zygotic Control (Paperback, Softcover reprint of the original 1st ed. 2017)
Loot Price: R4,521
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Vertebrate Development - Maternal to Zygotic Control (Paperback, Softcover reprint of the original 1st ed. 2017)
Series: Advances in Experimental Medicine and Biology, 953
Expected to ship within 10 - 15 working days
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This book provides a comprehensive overview of topics describing
the earliest steps of fertilization, from egg activation and
fertilization to the activation of the zygotic genome, in various
studied vertebrate model systems. The contribution of maternal and
paternal factors and their role in the early embryo as parental DNA
becomes modified and embryonic genes become activated is
fundamental to the initiation of embryogenesis in all animal
systems. It can be argued that this is a unique developmental
period, when information from the parents is compressed to direct
the development of the body plan of the entire organism, a process
of astounding simplicity, elegance and beauty. In addition to their
fundamental scientific interest, many frontiers of biomedicine,
such as reproductive biology, stem cells and reprogramming, and the
understanding of intergenerational diseases, depend on advances in
our knowledge of these early processes. Vertebrate Development:
Maternal to Zygotic Control brings together chapters from experts
in various disciplines describing the latest advances related to
this important developmental transition. Each chapter is a
synthesis of knowledge relevant to all vertebrates, with details on
specific systems as well as comparisons between the various studied
vertebrate models. The editorial expertise encompasses the fields
of major vertebrate model systems (mammalian, amphibian and
teleost) ensuring a balanced approach to various topics. This
unique book-with its combination of in-depth and up-to-date basic
research, inter-species comprehensiveness and emphasis on the very
early stages of animal development-is essential for research
scientists studying vertebrate development, as well as being a
valuable resource for college educators teaching advanced courses
in developmental biology.
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