Thiamine: Catalytic Mechanisms in Normal and Disease States brings
together the most recent developments in thiamine diphosphate
(TDP)-requiring enzyme research and details the mechanisms of
catalysis and structure-function relationships, as well as
pathophysiological aspects of a spectrum of diseases associated
with TDP-requiring enzymes. Providing new insights into
neurogenerative diseases, this volume associates defects in the
function of TDP-dependent enzymes with numerous metabolic disorders
and disease states and offers novel aspects of thiamine enzymes in
chiral synthesis as well as new perspectives on the cellular role
of thiamine triphosphate and thiamine triphosphates.
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