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Books > Medicine > Clinical & internal medicine > Neurology & clinical neurophysiology
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Progress in Parkinson Research (Hardcover, 1988 ed.)
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Progress in Parkinson Research (Hardcover, 1988 ed.)
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In the past five years significant progress has been made in our
basic and clinical under- standing of Parkinson's disease. The
discovery that MPTP, a relatively simple molecule, is able to
induce parkinsonism in otherwise healthy adult humans, and the
recent interest in the possibility of "transplantation" procedures
as a therapeutic modality in the treatment of Parkin- son's disease
have generated enormous interest in research related to Parkinson's
disease. In this setting, the National Parkinson Foundation decided
to organize a research meeting to bring together scientists
actively engaged in research relevant to the study of Parkinson's
disease, to accelerate its progress and to promote an exchange of
ideas. This meeting took place in Janu- ary 1988 at Key Biscayne,
Florida. It was decided to publish the proceedings ofthis meeting
to allow rapid documentation of the participants current findings
and views regarding this rapidly of this volume follows the
organization of the meeting and begins evolving field. The
structure with a clinical and neuropathological review of current
knowledge regarding Parkinson's dis- ease. Since dopaminergic
neurons playa major role in the pathophysiology of the disease,
many of the contributions relate to some aspects of dopaminergic
function including localiza- tion, regulation, and pharmacology of
dopamine receptors. A special effort has been made to provide a
summary of the present knowledge of the cellular biology of the
dopaminergic neurons.
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